Table 2 Association of Infant and Maternal Demographic Characteristics with SARS-CoV-2 Antibody Reactivity Using Logistic Regression.

From: Longitudinal analysis of passively and actively acquired SARS-CoV-2 antibodies in infants with repeat newborn screening samples

Parameter

Estimate

Std. error

z value

p-value

Odds ratio (95% CI)

Intercept

− 1.3691

0.0238

− 57.6

 < 2E−16

0.254 (0.243–0.266)

Multiple births

− 0.1329

0.0237

− 5.6

2.16E−08

0.876 (0.836–0.917)

Maternal age

 20–30 y

− 0.0303

0.0241

− 1.3

0.21

0.970 (0.926–1.017)

 > 30 y

0.1400

0.0240

5.8

5.18E−09

1.150 (1.098–1.206)

Female sex

0.0122

0.0075

1.6

0.11

1.012 (0.997–1.027)

Gestational age

 20–36 wk

0.0025

0.0173

0.1

0.88

1.003 (0.969–1.037)

Birthweight

 < 1500 g

− 0.0028

0.1000

− 0.03

0.98

0.997 (0.817–1.209)

 1500–2499 g

− 0.0554

0.0215

− 2.6

0.010

0.946 (0.907–0.987)

Repeat specimens

− 0.0736

0.0149

− 4.9

7.95E−07

0.929 (0.902–0.957)

Birthweight < 1500 g * Repeat specimens

− 0.3975

0.1084

− 3.7

0.0002

0.672 (0.545–0.834)

Birthweight 1500–2499 g * Repeat specimens

− 0.0081

0.0334

− 0.2

0.81

0.992 (0.929–1.059)

  1. y years of age, wk weeks, g grams; * indicates interaction term. Parameter estimates, standard errors, and associated p-values are reported here. Reference parameters include male, single birth, maternal age < 20 y, > 36 wk gestational age, birthweight > 2500 g and single collected infants.
  2. Significant values are in (bold).
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