Table 2 Local control (LC), progression-free survival (PFS), and overall survival (OS) according to clinical and treatment-related parameters.
Parameter | LC | PFS | OS | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Median | 6m | 12m | 24m | Median | 6m | 12m | 24m | Median | 6m | 12m | 24m | |
Dose (Gy) | ||||||||||||
15 | 8 | 80 | 20 | N/O | 6 | 50 | 9.1 | N/O | 11 | 90 | 36 | 9.1 |
20 | 13 | 91 | 63 | 0 | 10 | 70 | 23 | 0 | 14.5 | 100 | 64 | 23 |
25 | 17 | 97.5 | 68 | 8 | 11.5 | 80 | 48 | 2.4 | 17.5 | 100 | 68 | 17 |
Extrahepatic metastases | ||||||||||||
Yes | Not tested | Not tested | Not tested | Not tested | 11 | 52 | 24 | N/O | 12.5 | 100 | 80 | 28 |
No | 7.5 | 80 | 39 | 2 | 17 | 96 | 50 | 17 | ||||
Lung metastases | ||||||||||||
Yes | Not tested | Not tested | Not tested | Not tested | 10.5 | 76 | 35 | N/O | 14 | 95 | 59 | 18 |
No | 9 | 86 | 46 | 2 | 17.5 | 100 | 72 | 26 | ||||
Abdominal metastases | ||||||||||||
Yes | Not tested | Not tested | Not tested | Not tested | 6 | 42 | N/O | N/O | 10 | 100 | 29 | 14 |
No | 10.5 | 85 | 48 | 1.5 | 16.5 | 100 | 73 | 26 | ||||
Number of metastases | ||||||||||||
1 | 19 | 81 | 61 | 0 | 11 | 82 | 47 | 0 | 20 | 100 | 76 | 29 |
2 | 14 | 90 | 62 | N/O | 10 | 89 | 33 | N/O | 17 | 100 | 55 | 12 |
3 | 12 | 100 | 67 | 17 | 11 | 100 | 33 | 5.6 | 14 | 100 | 67 | 22 |
4 | 17 | 100 | 66 | N/O | 4 | 43 | 14 | N/O | 11 | 84 | 43 | 0 |
Largest mean size of tumours treated during one procedure | ||||||||||||
≤ 4 cm | 22 | 85 | 77 | 0 | 14 | 79 | 57 | 0 | 17 | 100 | 78 | 19 |
> 4cm | 10 | 96 | 52 | N/O | 9 | 85 | 34 | N/O | 14 | 100 | 58 | 25 |
Number of lines of chemotherapy | ||||||||||||
No more than 3 | 18 | 94 | 76 | 14 | 10 | 84 | 37 | 2 | 16 | 98 | 66 | 24 |
4 and more | 17 | 94 | 59 | 6 | 13 | 73 | 62 | 0 | 17 | 100 | 78 | 24 |
Grade | ||||||||||||
1 | 9 | 78 | 75 | N/O | 8.5 | 64 | 28 | 0 | 17.5 | 100 | 57 | 20 |
2 | 19 | 95 | 37 | 0 | 13 | 85 | 60 | 0 | 18.5 | 100 | 79 | 36 |
3 | 7 | 63 | N/O | N/O | 6.5 | 100 | 0 | N/O | 9.5 | 100 | 25 | 0 |
RAS mut | ||||||||||||
Yes | 13 | 93 | 63 | 5 | 10 | 88 | 40 | 2 | 17 | 96 | 66 | 17 |
No | 19 | 90 | 61 | 22 | 10 | 78 | 47 | 0 | 18 | 94 | 74 | 36 |
