Fig. 3

Original and synthesized RPE-melanin OCT imaging of serous PED in the left eye of a 56-year-old man. (a) SW-AF and (b) NIR-AF images show hyper-AF lesions. (a) In the SW-AF image, the hyper-AF lesion is partially obscured in the foveal region (red arrow). (c) En face projection image of standard OCT. The red line indicates the margin of the PED, and the yellow line indicates the scanning positions for B-scan images in (d–f). (d) The standard OCT B-scan image shows intraretinal hyperreflective foci within the hyper-AF lesion. Both the (e) original and (f) synthesized RPE-melanin B-scan images reveal intraretinal RPE-melanin migration. The (g) original and (h) synthesized RPE-melanin thickness maps are similar to the (b) NIR-AF image, with RPE-melanin thickness clearly visualized in (i,j) the color-coded maps. (k) En face distribution of originalRPE70. (l) En face distribution of synRPE70.