Fig. 3 | Scientific Reports

Fig. 3

From: Distinct white matter alteration patterns in post-infectious and gradual onset chronic fatigue syndrome revealed by diffusion MRI

Fig. 3The alternative text for this image may have been generated using AI.

The multiple regression results of axial diffusivity (AD) with physical component summary (PCS) among all participants in the post-infectious ME/CFS (PI-ME/CFS) group. Results are displayed in Montreal Neurological Institute (MNI) 152 standard space based on the reference FSL_HCP1065 fractional anisotropy 1 × 1 × 1 mm standard-space image. The top row shows the results from six different axial slices, where the z-coordinates in MNI space from left to right are z = −12 mm, −2 mm, 8 mm, 18 mm, 28 mm, and 38 mm, respectively. The middle row shows the results from six different coronal slices, where the y-coordinates in MNI space from left to right are y = −46 mm, −36 mm, −26 mm, −16 mm, −6 mm, and 4 mm, respectively. The bottom row shows the results from six different sagittal slices, where the x-coordinates in MNI space from left to right are x = −35 mm, −20 mm, −5 mm, 10 mm, 25 mm, and 40 mm, respectively. Blue-green clusters show the significant negative correlation of AD with PCS for all participants in the PI-ME/CFS group. The colour bar represents 1-p values, with higher values indicating greater levels of statistical significance.

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