Fig. 3 | Scientific Reports

Fig. 3

From: Effect of continuous Ia fibre activity suppression on hyperreflexia-related spasticity and maladaptive synaptic connections in the spinal cord after injury

Fig. 3

(R,S)-3,5-dihydroxyphenylglycine (DHPG) group reappear Hoffman’s reflex (H-reflex) Rate Dependent Depression (RDD). (A) Scheme of experience schedule. Drugs were administered for 2 weeks at 1w post-spinal cord injury (SCI). (B,C) Graph of H-reflex’s change in depression comparing SCI-vehicle (blue) and SCI-DHPG (red). SCI-vehicle n = 9, SCI-DHPG n = 9. (D,E) Graph of H-reflex’s change in depression comparing pre-SCI (D,E, white), SCI-vehicle (D, blue), and SCI-DHPG (E, red). Data are represented as mean ± S.E.M. Pre-SCI n = 18, each drug group n = 9. Shapiro–Wilk test, ANOVA, Tukey–Kramer (**p < 0.01, ***p < 0.001).

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