Table 2 Mortality and multivariate Cox regression assessing the association between IBI and incident all-cause and cancer-specific mortality.
Outcomes | Variables | Mortality (%) | Person-years | Incidence/1000 person-years | Hazard ratio (95% CI) | |||||
|---|---|---|---|---|---|---|---|---|---|---|
Crude | P value | Model 1 | P value | Model 2 | P value | |||||
All-cause mortality | IBI (Per SD increase) | 3483 (23.48) | 223719.71 | 15.57 | 1.468 (1.406–1.533) | < 0.001 | 1.276 (1.222–1.331) | < 0.001 | 1.234 (1.179–1.291) | < 0.001 |
Quartiles of IBI | ||||||||||
Quartile 1 | 532 (14.34) | 58499.24 | 9.09 | 1 | 1 | 1 | ||||
Quartile 2 | 858 (23.13) | 56319.1 | 15.23 | 1.675 (1.471–1.909) | < 0.001 | 1.128 (0.996–1.279) | 0.058 | 1.116 (0.983–1.268) | 0.089 | |
Quartile 3 | 1082 (29.16) | 54957.25 | 18.71 | 2.175 (1.923–2.460) | < 0.001 | 1.290 (1.144–1.456) | < 0.001 | 1.244 (1.106-1.400) | < 0.001 | |
Quartile 4 | 1065 (28.72) | 53944.17 | 19.74 | 2.749 (2.414–3.130) | < 0.001 | 1.689 (1.516–1.881) | < 0.001 | 1.555 (1.382–1.751) | < 0.001 | |
P for trend | < 0.001 | < 0.001 | < 0.001 | |||||||
Cancer mortality | IBI (Per SD increase) | 778 (5.24) | 223719.71 | 3.48 | 1.348 (1.245–1.461) | < 0.001 | 1.178 (1.081–1.284) | < 0.001 | 1.141 (1.045–1.246) | 0.004 |
Quartiles of IBI | ||||||||||
Quartile 1 | 135 (3.64) | 58499.24 | 2.31 | 1 | 1 | 1 | ||||
Quartile 2 | 210 (5.66) | 56319.1 | 3.73 | 1.501 (1.106–2.037) | 0.010 | 1.059 (0.780–1.439) | 0.707 | 1.018 (0.740–1.402) | 0.910 | |
Quartile 3 | 212 (5.71) | 54957.25 | 3.86 | 2.023 (1.469–2.786) | < 0.001 | 1.288 (0.934–1.778) | 0.121 | 1.214 (0.876–1.682) | 0.240 | |
Quartile 4 | 221 (5.96) | 53944.17 | 4.10 | 2.149 (1.651–2.796) | < 0.001 | 1.420 (1.123–1.797) | 0.004 | 1.295 (1.008–1.662) | 0.043 | |
P for trend | < 0.001 | 0.002 | 0.017 | |||||||