Table 3 ROC and reclassification analysis evaluating the usefulness of IBI to improve the risk stratification of incident all-cause and cancer-specific mortality.

From: Inflammatory burden index predicts long term mortality in a nationally representative population from NHANES

Outcomes

Model

AUC (95% CI)

P value

P for comparison

NRI (continuous)

P value

IDI

P value

All-cause mortality

IBI

0.708 (0.701–0.716)

< 0.001

–

–

–

–

–

Conventional risk factors*

0.807 (0.802–0.812)

< 0.001

–

–

–

–

–

Conventional risk factors + IBI

0.808 (0.803–0.813)

< 0.001

0.012

0.200 (0.167–0.234)

< 0.001

0.003 (0.002–0.005)

< 0.001

Cancer mortality

IBI

0.632 (0.625–0.640)

< 0.001

–

–

–

–

–

Conventional risk factors*

0.791 (0.785–0.798)

< 0.001

–

–

–

–

–

Conventional risk factors + IBI

0.799 (0.793–0.806)

< 0.001

< 0.001

0.138 (0.103–0.279)

< 0.001

0.008 (0.005–0.010)

< 0.001

  1. *Conventional risk factors: age, sex, race, current smoking, current drinking, PIR, BMI, WC, TC, triglycerides, Scr, hypertension, diabetes, and cancer morbidity.
  2. ROC, receiver operating characteristic curve; IBI, inflammatory burden index; AUC, area under the curve; CI, confidence interval; NRI, net reclassification improvement; IDI, integrated discrimination index; BMI, body mass index; WC, waist circumference; TC, total cholesterol; Scr, serum creatinine.
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