Table 1 Clinical characteristics of 97 ICC Patients.

From: Hepatic arterial infusion chemotherapy with Folfox 4 regimen versus cisplatin and gemcitabine for locally advanced intrahepatic cholangiocarcinoma

Characteristics

HAIC group (n = 37 )

CisGem group (n = 60)

P value

Age, years, median (range)

48 (37–72)

49 (37–73)

0.507

Sex

   

 Male

24 (64.9%)

40 (66.7%)

> 0.999

 Female

13 (35.1%)

20 (33.3%)

ECOG

   

 0

24 (64.9%)

24 (40%)

0.022

 1

13 (35.1%)

36 (60%)

Tumor number

   

 Single

14 (37.8%)

18 (30%)

0.506

 Multiple

23 (62.2%)

42 (70%)

Largest tumor size, cm

   

 < 5

10 (27.0%)

15 (25%)

0.816

 ≥ 5

27 (73.0%)

45 (75%)

Local lymph node metastasis

   

 Absent

12 (32.4%)

16 (26.7%)

0.636

 Present

25 (67.6%)

24 (73.3%)

Liver cirrhosis

   

 Absent

31 (83.8%)

48 (80%)

0.789

 Present

6 (16.2%)

12 (20%)

Child-Pugh score

   

 A

26 (70.3%)

43 (71.7%)

> 0.999

 B

11 (29.7%)

17 (28.3%)

CEA, ng/mL, median (range)

15.4 (1.1–79.3)

10.3 (1.2–112.2)

0.888

CA199, U/mL, median (range)

293 (13–1169)

254 (23–3244)

0.492

ALT, U/L, median (range)

36 (24–64)

34.5 (22–67)

0.920

AST, U/L, median (range)

37 (22–58)

35.5 (18–75)

0.934

Albumin, g/L, median (range)

38 (34–42)

38.5 (32–43)

0.760

Total Bilirubin, umol/L,

median (range)

20.5 (11.7–42.1)

16.4 (9.5–41.2)

0.001

Curative resection

3 (8.1%)

2 (3.3%)

0.366

  1. Data are No. (%) unless otherwise specified.
  2. HAIC, hepatic arterial infusion chemotherapy; CisGem, cisplatin plus gemcitabine; ECOG, Eastern Cooperative Oncology Group; CEA, carcinoembryonic antigen; CA-199, carbohydrate antigen 199; ALT, alanine aminotransferase; AST, aspartate aminotransferase.