Fig. 3 | Scientific Reports

Fig. 3

From: Pharmacokinetic and pharmacodynamic characterization of remimazolam in older Japanese adults who underwent general anesthesia at early stage of infusion

Fig. 3

Prediction-corrected visual predictive check plot of the final pharmacokinetic and pharmacodynamic model. Open circles show the observed plasma concentrations (a and b) or bispectral index (BIS) (c) The top dotted, middle solid, and bottom dotted lines represent the 95th, 50th, and 5th percentiles, respectively, calculated from 1000 simulated datasets.

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