Fig. 5 | Scientific Reports

Fig. 5

From: Constitutive interaction between neutrophils and von Willebrand factor in peripheral blood

Fig. 5

Association of human neutrophils and VWF in peripheral blood. (A) Representative flow cytometry histogram showing VWF presence on the surface of human neutrophils. (B) Statistical comparison of VWF-positive neutrophil percentages between human and mouse peripheral blood samples. (C) Statistical analysis of VWF levels on human neutrophils from male and female participants. (D) Correlation analysis of the relationship between VWF levels (mean fluorescence intensity, MFI) on human neutrophils and participant age (years); each data point representing an individual, with the solid line shows the line of best fit. Pearson correlation coefficient (r) = 0.2431, n = 23. (E) Correlation analysis between the percentage of VWF-bound neutrophils and total neutrophil count. Each data point represents an individual, with the solid line indicating the line of best fit. Pearson correlation coefficient (r) = 0.0286; n = 23. (F)Statistical comparison of VWF levels on neutrophils from individuals with blood types O and non-O. Statistical analyses were conducted using t-tests for pairwise comparisons, with significance indicated as ****p < 0.0001, **p < 0.01, and “n.s.” for not significant.

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