Table 1 Matrix metalloproteinase 8 (MMP-8) expression patterns in neoadjuvant therapy (NAT) and up-front surgery groups. Linear-by-linear test* was used for ordinal variables and Chi square test was applied for categorical variables. P-value < 0.05 was considered significant.
Up-front surgery (n = 141) | NAT (n = 113) | p-value | |
|---|---|---|---|
MMP-8 expression | |||
0 = non-detectable | 6 (4.3) | 2 (1.8) | |
1 = low | 22 (15.6) | 34 (30.1) | |
2 = moderate | 65 (46.1) | 33 (29.2) | |
3 = high | 48 (34.0) | 44 (38.9) | 0.663* |
MMP-8 low vs. high | |||
Low expression | 28 (19.9) | 36 (31.9) | |
High expression | 113 (80.1) | 77 (68.1) | 0.029 |
MMP-8 negative vs. positive | |||
Negative expression | 6 (4.3) | 2 (1.8) | |
Positive expression | 135 (95.7) | 111 (98.2) | 0.260 |