Fig. 1
From: Adenosine stress myocardial perfusion imaging and myocardial work in evaluating INOCA

Quantitative analysis of contrast echocardiography of the left ventricular lateral wall in the INOCA group: After the drug load test (b), the contrast agent filling rate was significantly slower (Wash-in Slope 0.09 dB/s) compared to before the test (a), the time to peak was delayed (TTP 13.40 s), the peak intensity was reduced (Peak Intensity 1.27 dB), and the total contrast agent flow was significantly decreased (AUC 8.3 dB·s). This perfusion pattern (One Minus Exp curve) highly suggests that there is myocardial blood flow perfusion impairment in this area, and the possible cause may be microcirculation dysfunction. (a) Myocardial perfusion time-intensity curve of the left ventricular lateral wall in INOCA patients before drug stress test. (b) Myocardial perfusion time-intensity curve of the left ventricular lateral wall in INOCA patients after drug stress test.