Table 1 Clinical characteristic of patients in the study stratified by high-risk phenotypes.
From: Metabolomic and cytokine profiles of high-risk sepsis phenotypes in children
PHES | MODS control | p-value | |
|---|---|---|---|
Number | 17 (34%) | 33 (66%) | |
Median age (months) | 76 (17–142) | 32 (12–87) | p = 0.45 |
Gender (%Male) | 41% | 52% | p = 0.35 |
White | 11 (65%) | 13 (39%) | p = 0.51 |
Hispanic | 4 (23%) | 10 (30%) | p = 0.48 |
African American | 1 (6%) | 7 (21%) | p = 0.16 |
Asian | 0 (0%) | 1 (3%) | p = 0.66 |
American Indian | 0 (0%) | 1 (3%) | p = 0.66 |
Other | 5 (29%) | 9 (27%) | p = 0.59 |
Unknown/Did not answer | 0 (0%) | 2 (6%) | p = 0.43 |
pSOFA (Day 0) | 9 (6-10.75) | 5 (3.75-8) | p = 0.001 |
pSOFA (Day 2) | 7.5 (5.25–8.75) | 3.5 (2.75-6) | p < 0.00001 |
Median LOS days | 21.1 (10.2–27.7) | 13.9 (9-21.4) | 0.3 |
Deaths | 2 (12%) | 1 (3%) | p = 0.26 |
PMODS | 7 (41%) | 7 (21%) | p = 0.054 |
PMODS | MODS control | p-value | |
|---|---|---|---|
Number | 14 (28%) | 36 (72%) | |
Median age (months) | 79 (37–115) | 28 (12–112) | p = 0.11 |
Gender (%Male) | 36% | 53% | p = 0.13 |
White | 8 (57%) | 14 (39%) | p = 0.20 |
Hispanic | 2 (14%) | 10 (28%) | p = 0.27 |
African American | 2 (14%) | 6 (17%) | p = 0.60 |
Asian | 0 (0%) | 1 (3%) | p = 0.72 |
American Indian | 1 (7%) | 0 (0%) | p = 0.28 |
Other | 3 (21%) | 10 (28%) | p = 0.47 |
Unknown/Did not answer | 0 (0%) | 2 (6%) | p = 0.51 |
pSOFA (Day 0) | 9 (8-11.75) | 5 (3.75-7) | p < 0.001 |
pSOFA (Day 2) | 7 (6.25-9) | 4 (2.75–5.25) | p < 0.001 |
Median LOS days | 27.7 (11.2–21.6) | 12.1 (9.7–21.2) | p = 0.38 |
Deaths | 3 | 0 | p = 0.02 |
PHES phenotype | 7 (50%) | 10 (28%) | p = 0.18 |
