Fig. 1 | Scientific Reports

Fig. 1

From: Integrated bioinformatics identifies ferroptosis biomarkers and therapeutic targets in idiopathic pulmonary arterial hypertension

Fig. 1

Identification of DE-FRGs from the GSE48149. (A) Visualization of 15 downregulated and 12 upregulated genes between IPAH and normal samples using a heatmap. (B) Associations between DE-FRGs, with no correlation between ADAM23 and SRC and any other DE-FRGs. C and D. GO enrichment and Reactome pathway analyses were employed to elucidate DE-FRG-associated biological functions and pathways. E and F. Reactome pathway analyses revealed remarkable enrichment in fluid shear stress, atherosclerosis, hepatocellular carcinoma, and chemical carcinogenesis reactive oxygen species.

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