Table 1 Twenty-seven DE-FGRS of 237 FRGs with 15 down-regulated and 12 up-regulated genes in GSE48149.

From: Integrated bioinformatics identifies ferroptosis biomarkers and therapeutic targets in idiopathic pulmonary arterial hypertension

DE-FGRS

Con Mean

Treat Mean

P-value

Type

TF

7.694373

8.4974365

0.00370218

Up

PGD

13.04663944

12.1850975

0.000575895

Down

TP53

8.520795111

8.042711125

0.000329083

Down

KEAP1

10.24850689

9.823452

0.000164541

Down

ULK2

7.649207444

7.845423875

0.007897984

Up

SOCS1

9.056795444

9.6826355

0.00246812

Up

MAPK14

7.900324556

7.597012875

0.001563143

Down

IFNG

7.208926333

9.201221875

0.000575895

Up

TNFAIP3

10.645038

12.82404025

0.000329083

Up

IDH1

12.21267922

11.32308813

0.00370218

Down

FADS1

11.09215022

9.91926825

0.000164541

Down

SLC25A28

11.96804178

12.51708963

0.000987248

Up

MFN2

10.87829122

10.52674388

0.007897984

Down

SMPD1

8.782253111

8.43587875

0.00246812

Down

USP11

9.837170778

10.26258975

0.000575895

Up

FADS2

8.553869778

7.924775875

0.00370218

Down

ADAM23

7.774517222

7.343884

0.005512135

Down

MEG3

9.803914889

10.81344388

0.000082270

Up

NQO1

10.31008733

9.484728375

0.000987248

Down

SLC3A2

10.94148889

10.162668

0.000987248

Down

SRC

9.538373889

9.81226825

0.007897984

Up

NFS1

8.638115444

9.236236375

0.007897984

Up

ENPP2

10.79377567

12.20948913

0.000164541

Up

CBS

10.45458022

9.443824375

0.000987248

Down

SREBF1

9.900411

9.25557975

0.00246812

Down

AHCY

12.02612433

11.47570063

0.000575895

Down

VDR

7.946485444

7.618824375

0.007897984

Down

PRDX1

13.97259856

13.466841

0.002421774

Down

COPZ1

11.71979467

11.35591175

0.00246812

Down

PARP10

9.291106333

9.657784

0.00370218

Up

PARP14

10.75779833

11.2985625

0.007897984

Up

BEX1

8.504673667

9.509029125

0.000987248

Up

MGST1

11.86885689

10.62353375

0.000164541

Down

DHODH

7.824816333

7.38555675

0.000575895

Down

PDK4

11.468836

13.4470235

0.000987248

Up

MAPKAP1

9.484097

9.0442895

0.002421774

Down

TERT

7.168574111

7.04489325

0.00246812

Down

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