Table 3 Reasons for discontinuing the drug.

From: Real world efficacy safety and drug survival of secukinumab over 6 years at the largest biological center in Poland

All discontinuations

66 (100%)

Ineffectiveness:

44 (66.7%)

 Primary

14 (21.2%)

 Secondary

30 (45.5%)

Type of ineffectiveness:

 Peripheral joints

24 (36.4%)

 Axial

12 (18.2%)

 Enthesitis

5 (7.6%)

 Psoriasis

5 (7.6%)

 Uveitis

2 (3%)

Adverse events:

18 (27.3%)

Infections

7 (10.6%)

 Respiratory tract

4 (6.1%)

 Skin

1 (1.5%)

 Gastrointestinal tract

1 (1.5%)

 Opportunistic

1 (1.5%)

Neurological

3 (4.5%)

Skin lesions

2 (3%)

Intolerance

2 (3%)

Neoplasm

2 (3%)

Allergy

1 (1.5%)

Other:

11 (16.7%)

 Resignation without giving a reason

5 (7.6%)

 Pregnancy or procreation plans

3 (4.5%)

 Change of treatment center

1 (1.5%)

 Administrative reasons

1 (1.5%)

 Willingness to participate in a clinical trial

1 (1.5%)