Fig. 6

Impact of XIAP overexpression on the effects of ANTP-SmacN7 and gamma ray in TPC−1 cells. (A) Expression levels of XIAP in TPC−1 cells and XIAP-overexpressing (XIAP-OE) TPC−1 cells. (B) q-PCR validation of XIAP expression in XIAP-OE TPC−1 cells. (C) Cell viability in TPC−1 cells with varying XIAP expression levels under treatment with ANTP-SmacN7 and gamma ray. (D) Comparative analysis of cell proliferation between different treatment groups, as assessed by colony formation assays. (E) Comparative analysis of cell migration between different treatment groups, as determined by Transwell assays. (F) The role of XIAP-OE and the effect of ANTP-SmacN7 on apoptosis in TPC−1 cells across experimental groups.(Error bars represent SD (n = 3). Statistical significance: *p < 0.05, **p < 0.01, ***p < 0.001.).