Table 1 In vitro anti-inflammatory activity of the synthesized compounds.

From: Synthesis, crystal structure, DFT calculations, in-vitro and in-silico studies of novel chromone-isoxazoline conjugates as antibacterial and anti-inflammatory agents

Samples

R

LOX-5 IC50 (mg/mL)

3

–

–

5a

4-CF3

1.163 ± 0.02a

5b

2-Cl

1.401 ± 0.03

5c

2-NO2

1.208 ± 0.01

5d

3,4,5-OCH3

–

5e

4-Br

0.951 ± 0.02

Quercetin

–

0.018 ± 0.007

  1. Tukey’s multiple range test indicates a non-significant difference between data with the same letter in the same test. (ANOVA, p < 0.05).
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