Table 2 GLM analysis on the association between BD or medication and hormones.

From: Independent and medication related effects of bipolar disorder on thyroid and reproductive hormones in women

Dependent variables

Model 1#

Model 2#

 

β

p

β

p

FT3

0.26

0.015

0.18

0.075

FT4

−0.03

0.806

−0.17

0.098

FT3/FT4

0.21

0.043

0.32

0.002

TSH

0.16

0.127

0.30

0.003

LH

0.27

0.010

0.06

0.591

FSH

−0.20

0.061

−0.01

0.953

LH/FSH

0.27

0.013

0.07

0.488

PRL

−0.14

0.189

0.00

0.970

E2

−0.13

0.227

0.11

0.290

TST II

−0.11

0.304

0.00

0.969

PRGE

−0.03

0.810

−0.16

0.136

AMH

0.18

0.099

0.30

0.004

Insulin

0.18

0.089

0.23

0.025

  1. # Model 1: conducted in drug-naïve BD patients and controls, BD diagnosis as independent variable, controlled for age, and history of drinking and smoking; Model 2: conducted in all BD patients, medication as independent variable, controlled for age, history of drinking and smoking, and duration of illness.
  2. GLM, General Linear Model; FT3,  free triiodothyronine; FT4, free thyroxine; TSH, thyroid stimulating hormone; ATF, abnormal thyroid function; LH, luteinizing hormone; FSH, follicle stimulating hormone; PRL, prolactin; E2, estradiol; TST II, testosterone II; PRGE, progesterone; AMH, anti-Müllerian hormone.
  3. Significance values are in bold.
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