Fig. 11

The key cell cluster ndothelial was analysed for proposed temporal trajectories. (a) Endothelia subgroup clustering UMAP plot; (b-d) Pseudo-temporal analysis of key cells, with dark blue in-dicating the early stages of differentiation and light blue representing the later stages of differen-tiation, where state 1 is the earliest period of differentiation; (e) Dynamic map of biomarker expression in proposed time series; top: AKR1C2, bottom: MAP1LC3A.