Fig. 4 | Scientific Reports

Fig. 4

From: AI-CMCA: a deep learning-based segmentation framework for capillary microfluidic chip analysis

Fig. 4The alternative text for this image may have been generated using AI.

Automated flow path analysis and efficiency gains in different CMC designs. (A) Quantitative flow analysis of a CMC with six parallel channels: (a) results for br0 and (b) results for br1, comparing system-generated and user-tracked data. (B) Flow tracking in a CMC with splitting and merging regions, showing system- and user-generated results across four branches. (C) Flow tracking in a tree-shaped CMC featuring ten merging points and fifteen splitting points, representing a real-life CMC with a complex channel network: (a) extracted datapoints and (b) a photograph of the CMC highlighting critical points in red circles and branch numbers in green. (D) Comparison of fluid front tracking accuracy between AI-CMCA-generated and manually selected user-annotated center points for both (a) simple straight-channel CMC and (b) more complex split-merge-serpentine CMC. (E) Total time required for analysis across different CMC designs such as (a) straight channels, (b) split/merge, (c) serpentine channels, (d) split merge serpentine, SARS-Cov-2-POC testing15and GFAP POC testing16highlighting the efficiency gains of the automated system over manually tracking.

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