Fig. 7 | Scientific Reports

Fig. 7

From: Bisphenol A suppresses colon epithelial cell responses via G0/G1-phase arrest, MAPK and PI3K/AKT pathway modulation, and MMP-2/9 Inhibition by upregulating p21WAF1

Fig. 7

p21WAF1 silencing reverses BPA-induced interference of proliferation and metastatic potential in colon epithelial cells. MTT (A) and cell counting (B) assays were performed in BPA-treated colon epithelial cells after p21WAF1 siRNA (si-p21) or scramble siRNA transfection. Wound-healing migration (C) and invasion assays (D) in BPA-treated colon epithelial cells following si-p21 or scramble siRNA transfection. All values from triplicate results are indicated as mean ± standard deviation. *p < 0.05 compared with control, #p < 0.05 compared with BPA treatment alone.

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