Fig. 7
From: Estrogen receptor α regulates SVCT2 protein level in human breast cancer cells
SVCT2 is involved in resistance to doxorubicin. MCF7 and T47D cells were transfected with scrambled siRNA or si-SVCT2 and treated with or without 0.5 mg/ml ascorbic acid and 200 μM doxorubicin for 24 h. (A, B) Cell viability was measured by the MTS. The results are representative of three independent experiments. Statistical significance was determined by Student’s t- test. (*p < 0.05, **p < 0.01 compared with the untreated group; #p < 0.05, ##p < 0.01 compared with single-drug treatment).
