Table 1 Baseline characteristics of the training, internal validation, and external validation cohorts.
Characteristic | Cohort | p value | ||
|---|---|---|---|---|
Training group (n = 155) | Internal validation group (n = 67) | External validation group (n = 197) | ||
Gender, n (%) | 0.241 | |||
Male | 104 (67.1%) | 37 (55.2%) | 125 (63.5%) | |
Female | 51 (32.9%) | 30 (44.8%) | 72 (36.5%) | |
Age (years) | 60.9 ± 11.6 | 59.6 ± 12.9 | 59.3 ± 11.6 | 0.433 |
pDoC, n (%) | 55 (35.5%) | 21 (31.3%) | 38 (19.3%) | 0.002 |
Time from onset to CT (h) | 2.0 (1.5, 2.5) | 1.6 (1.3, 2.3) | 2.1 (1.5, 2.4) | 0.156 |
Medical history, n (%) | ||||
Diabetes mellitus | 16 (10.3%) | 7 (10.4%) | 28 (14.2%) | 0.484 |
Coronary heart disease | 10 (6.5%) | 5 (7.5%) | 15 (7.6%) | 0.904 |
GCS score at admission | 6.0 (5.0, 8.0) | 5.0 (5.0, 7.0) | 6.0 (5.0, 7.0) | 0.538 |
Systolic blood pressure (mmHg) | 187.0 (167.0, 208.0) | 188.0 (166.0, 210.0) | 175.0 (154.0, 197.0) | 0.001 |
Diastolic blood pressure (mmHg) | 104.0 (94.0, 115.0) | 110.0 (98.0, 120.0) | 101.0 (91.0, 109.0) | < 0.001 |
Hematoma location, n (%) | 0.020 | |||
Basal ganglia | 130 (83.9%) | 45 (67.2%) | 151 (76.6%) | |
Thalamus | 25 (16.1%) | 22 (32.8%) | 46 (23.4%) | |
Hematoma volume (mL) | 50.0 (35.0, 70.0) | 40.0 (30.0, 60.0) | 50.0 (34.5, 70.0) | 0.047 |
mGS | 7.0 (0.0, 16.0) | 7.0 (0.0, 19.0) | 7.0 (0.0, 18.0) | 0.336 |
Cerebral hernia, n (%) | 47 (30.3%) | 28 (41.8%) | 71 (36.0%) | 0.229 |
Decompressive craniectomy, n (%) | 49 (31.6%) | 20 (29.9%) | 65 (33.0%) | 0.886 |
Operative methods, n (%) | < 0.001 | |||
Hematoma evacuation | 103 (66.5%) | 39 (58.2%) | 92 (46.7%) | |
Hematoma evacuation combined with EVD | 20 (12.9%) | 10 (14.9%) | 27 (13.7%) | |
Hematoma puncture drainage | 9 (5.8%) | 2 (3.0%) | 32 (16.2%) | |
Hematoma puncture drainage combined with EVD | 4 (2.6%) | 5 (7.5%) | 23 (11.7%) | |
EVD | 19 (12.3%) | 11 (16.4%) | 23 (11.7%) | |
Postoperative finding, n (%) | ||||
Postoperative rebleeding | 17 (11.0%) | 7 (10.4%) | 21 (11.7%) | 0.992 |
Intracranial infection | 19 (12.3%) | 6 (9.0%) | 16 (7.8%) | 0.418 |