Table 2 The association between parity and NAFLD.
No. of subjects | No. of NAFLD | NAFLD (%) | OR (95% CI) | |||||
|---|---|---|---|---|---|---|---|---|
Unadjusted | Model 1 | Model 2 | Model 3 | Model 4 | ||||
(A) Premenopausal | ||||||||
Parity | ||||||||
No | 3,083 | 330 | 10.7 | Reference | Reference | Reference | Reference | Reference |
Yes | 10,062 | 1,682 | 16.72 | 1.72 (1.49–2.00) | 1.03 (0.86–1.23) | 0.63 (0.48–0.83) | 0.65 (0.49–0.85) | 0.61 (0.46–0.80) |
P-value | < 0.001 | < 0.001 | 0.785 | 0.001 | 0.002 | 0.001 | ||
Number of parities | ||||||||
No parity | 3,083 | 330 | 10.7 | Reference | Reference | Reference | Reference | Reference |
1–2births | 5,778 | 811 | 14.04 | 1.47 (1.25–1.72) | 0.98 (0.81–1.18) | 0.62 (0.47–0.81) | 0.63 (0.48–0.84) | 0.59 (0.45–0.79) |
≥ 3 births | 4,284 | 871 | 20.33 | 2.09 (1.79–2.45) | 1.20 (0.98–1.47) | 0.67 (0.50–0.91) | 0.69 (0.51–0.94) | 0.64 (0.47–0.87) |
P-value | < 0.001 | < 0.001 | 0.005 | 0.003 | 0.005 | 0.002 | ||
(B) Postmenopausal | ||||||||
Parity | ||||||||
No | 241 | 66 | 27.39 | Reference | Reference | Reference | Reference | Reference |
Yes | 14,617 | 3,811 | 26.07 | 0.97 (0.70–1.36) | 0.98 (0.71–1.37) | 0.79 (0.52–1.20) | 0.76 (0.50–1.15) | 0.83 (0.52–1.30) |
P-value | 0.645 | 0.867 | 0.919 | 0.267 | 0.197 | 0.409 | ||
Number of parities | ||||||||
No parity | 241 | 66 | 27.39 | Reference | Reference | Reference | Reference | Reference |
1–2births | 3212 | 735 | 22.88 | 0.84 (0.60–1.18) | 0.83 (0.59–1.17) | 0.76 (0.49–1.16) | 0.72 (0.47–1.11) | 0.82 (0.51–1.31) |
≥ 3 births | 11,405 | 3076 | 26.97 | 1.01 (0.73–1.42) | 1.05 (0.75–1.46) | 0.80 (0.53–1.22) | 0.77 (0.51–1.18) | 0.83 (0.52–1.31) |
P-value | < 0.001 | 0.003 | < 0.001 | 0.389 | 0.290 | 0.707 | ||