Fig. 10

Molecular docking analysis of flavonoid compounds targeting hub proteins. (A) Heatmap illustrating binding affinities (kcal/mol) between six dietary flavonoids (Luteolin, Naringenin, Kaempferol, Epicatechin, Daidzein, Peonidin) and three hub targets (NLRC4, SPI1, NCF2). (B) Representative 3D structural models of six dietary flavonoids and three hub targets. Hydrogen bonds and hydrophobic interactions are highlighted in dashed lines and surface shading, respectively.