Table 4 Regression analysis of late outcomes associated with bronchopulmonary dysplasia severity in extremely preterm infants.
From: Outcomes of extremely preterm infants with bronchopulmonary dysplasia: a retrospective cohort study
Variables | N (%) | Odds Ratio (unadjusted) | 95% CI | P |
|---|---|---|---|---|
Outcome: Inhaled corticosteroids (N = 52) | ||||
Mild BPD | 8 (44.4) | 4.10 | 1.40–11.99 | 0.010 |
Moderate BPD | 22 (39.2) | 3.32 | 1.55–7.08 | 0.002 |
Severe BPD | 6 (60) | 7.69 | 1.94–30.37 | 0.004 |
No BPD | 16 (16.3) | 1.0 | ||
Outcome: Systemic corticosteroids (N = 35) | ||||
Mild BPD | 6 (35.3) | 6.07 | 1.77–20.76 | 0.004 |
Moderate BPD | 15 (26.8) | 4.07 | 1.59–10.36 | 0.003 |
Severe BPD | 6 (60%) | 16.68 | 3.88–71.67 | < 0.001 |
No BPD | 8 (8.2) | 1.00 | ||
Outcome: PICU admission (any) (N = 11) | ||||
Mild BPD | 1 (6.3) | 6.00 | 0.35–101.18 | 0.214 |
Moderate BPD | 7 (13) | 13.40 | 1.60–112.21 | 0.017 |
Severe BPD | 2 (22.2) | 25.71 | 2.07–319.79 | 0.012 |
No BPD | 1 (1.1) | 1.00 | ||
Outcome: Pulmonary hypertension (N = 13) | ||||
Mild BPD | 0 (0.0) | 0.00 | 0.000 – . | 0.999 |
Moderate BPD | 6 (10.5) | 11.88 | 1.39–101.36 | 0.024 |
Severe BPD | 6 (60.0) | 151.50 | 14.58–1574.27 | < 0.001 |
No BPD | 1 (1.0) | 1.0 | ||
Outcome: Any PDA device closure (N = 12) | ||||
Mild BPD | 1 (5.3) | 2.75 | 0.24–31.94 | 0.419 |
Moderate BPD | 7 (12.3) | 6.93 | 1.39–34.59 | 0.018 |
Severe BPD | 2 (20) | 12.37 | 1.53–99.87 | 0.018 |
No BPD | 2 (2.0) | 1.0. | ||
Outcome: Home gastric tube feeding (N = 7) | ||||
Mild BPD | 0 (0.0) | 0.00 | 0.00 – . | 0.999 |
Moderate BPD | 2 (3.5) | 3.67 | 0.32–41.42 | 0.293 |
Severe BPD | 4 (40.0) | 67.33 | 6.48–699.67 | < 0.001 |
No BPD | 1 (1.0) | 1.00 | ||
Outcome: Motor delay (N = 37) | ||||
Mild BPD | 5 (50.0) | 2.90 | 0.94–8.89 | 0.062 |
Moderate BPD | 6 (31.6) | 2.05 | 0.89–4.67 | 0.089 |
Severe BPD | 14 (24.6) | 6.28 | 1.61–24.54 | 0.008 |
No BPD | 14 (13.4) | 1.00 | ||
Outcome: Expressive delay (N = 57) | ||||
Mild BPD | 3 (15.8) | 0.55 | 0.15–2.03 | 0.369 |
Moderate BPD | 22 (38.6) | 1.84 | 0.92–3.68 | 0.086 |
Severe BPD | 6 (60.0) | 4.38 | 1.14–16.76 | 0.031 |
No BPD | 26 (25.5) | 1.00 | ||
Outcome: Any neurodevelopmental delay risk (N = 67) | ||||
Mild BPD | 9 (47.4) | 2.16 | 0.79–5.85 | 0.130 |
Moderate BPD | 33 (57.9) | 3.30 | 1.67–6.49 | < 0.001 |
Severe BPD | 7 (70.0) | 5.60 | 1.35–23.12 | 0.0147 |
No BPD | 30 (29.4) | 1.00 | ||
