Table 1 Docking score of potential components with three targets.

From: Rosa roxburghii Tratt fruit extract ameliorate free fatty acid induced steatosis in HepG2 cells through activating PI3K-Akt and PPAR pathways

Components

Affinity (kcal/mol)

AKT1

PPARA

PPARG

Naringenin chalcone

−8.2

−7.3

−7.6

Ethyl caffeate

−7.5

−6.7

−6

Caffeic acid

−7.3

−6.6

−6.1

Tryptophan

−7.9

−6.5

−6.4

L-Tryptophan

−7.9

−6.5

−6.4

L-Tyrosine

−6.6

−6.3

−5.9

L-Glutamic acid

−5

−5.3

−5.4

p-Coumaric acid

−6.7

−6.3

−5.7

3-phenyllactic acid

−6.8

−6.2

−6.3

Meglutol

−5.3

−5.2

−4.8

D-(+)-Malic acid

−5

−5.6

−5.5