Table 2 Univariate and multivariate analyses of survival in patients with ESCC following esophagectomy using the Cox proportional hazards model.

From: Low levels of tumor suppressor miR-3619 in plasma contribute to malignant outcomes and a target for nucleic acid therapy in esophageal cancer

Variable

Univariate analysis a

Multivariate analysis b

P-value

HR c

95% CI d

P-value

Sex

Male vs. female

0.639

  

–

  

Age (years)

70 ≤ vs. < 70

0.284

  

–

  

Histological type

Poorly vs. well or moderately differentiated

0.480

  

–

  

Tumor size (mm)

50 ≤ vs. < 50

0.503

  

–

  

Lymphatic invasion

Present vs. absent

0.729

  

–

  

Venous invasion

Present vs. absent

0.606

  

–

  

T-stage

T2/3/4 vs. T1

0.265

4.49

1.5

–

13.2

0.007

N-stage

N1/2/3 vs. N0

0.011

8.59

2.7

–

27.4

< 0.001

Plasma miR-3619-5p level

Low vs. high

0.047

2.09

1.1

–

4.0

0.028

  1. aUnivariate survival analysis was performed using the Kaplan–Meier method; the significance was determined by the log-rank test. bMultivariate survival analysis was performed using the Cox proportional hazards model. cHR: hazard ratio. dCI: confidence interval.
  2. Note: significant values are shown in bold.
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