Table 6. Summary of results from experimental session three, presented as mean and standard deviations for each outcome measure, across groups (cerebellar patients and controls), stimuli (music and metronome) and conditions (Adaptive, Non-Adaptive, Silence). PwCA: persons with cerebellar ataxia; HC: healthy controls, Min: minutes.

From: Temporal prediction and feedforward control in cerebellar ataxia during spontaneous, instructed, and adaptive auditory-motor coupling while walking

Outcome measures

Group

Adaptive metronome condition

Adaptive music condition

Non-adaptive metronome condition

Non-Adaptive music condition

Silence condition

Min 1-2

Min 3-4

Min 5-6

Min 7-8

Min 1-2

Min 3-4

Min 5-6

Min 7-8

Min 1-2

Min 3-4

Min 5-6

Min 7-8

Min 1-2

Min 3-4

Min 5-6

Min 7-8

Min 1-2

Min 3-4

Min 5-6

Min 7-8

Resultant Vector Length [0-1]

PwCA

0.86 ± 0.20

0.85 ± 0.20

0.80 ± 0.21

0.80 ± 0.23

0.80 ± 0.20

0.81 ± 0.17

0.81 ± 0.23

0.79 ± 0.20

0.69 ± 0.29

0.75 ± 0.31

0.68 ± 0.33

0.64 ± 0.32

0.61 ± 0.33

0.60 ± 0.31

0.69 ± 0.31

0.63 ± 0.29

-

HC

0.94 ± 0.04

0.96 ± 0.02

0.94 ± 0.05

0.96 ± 0.04

0.91 ± 0.07

0.88 ± 0.013

0.82 ± 0.18

0.87 ± 0.12

0.90 ± 0.06

0.92 ± 0.07

0.87 ± 0.14

0.81 ± 0.26

0.74 ± 0.25

0.77 ± 0.19

0.75 ± 0.26

0.65 ± 0.30

-

Relative Phase Angle [degrees]

PwCA

-38.15 ± 30.85

-31.13 ± 50.68

-21.53 ± 55.89

-34.24 ± 66.79

-24.28 ± 49.41

-12.39 ± 33.59

-12.93 ± 42.08

-10.64 ± 40.68

-44.45 ± 43.23

-50.28 ± 43.32

-18.65 ± 27.35

-36.56 ± 57.14

-8.47 ± 47.51

1.72 ± 64.16

-

-8.33 ± 60.56

23.08 ± 55.08

-

-

HC

-36.81 ± 19.08

-28.56 ± 18.85

-26.01 ± 22.76

-30.56 ± 24.48

-10.86 ± 45.38

2.68 ± 36.37

-2.48 ± 55.73

-16.11 ± 50.94

-45.03 ± 32.61

-34.44 ± 30.57

-36.23 ± 39.87

-38.70 ± 48.90

-20.06 ± 49.25

-19.42 ± 36.73

-6.74 ± 31.87

-6.05 ± 32.15

-

Alpha [0-1]

PwCA

0.83 ± 0.28

0.83 ± 0.28

0.49 ± 0.25

0.65 ± 0.27

0.80 ± 0.16

HC

0.62 ± 0.21

0.88 ± 0.30

0.33 ± 0.25

0.70 ± 0.27

0.84 ± 0.25

Cadence mean [steps/min]

PwCA

98.81 ± 9.51

98.19 ± 9.58

95.07 ± 7.01

94.69 ± 8,59

97.25 ± 8.66

97.92 ± 7.78

95.88 ± 9.18

94.65 ± 9.711

98.60 ± 10.43

98.15 ± 10.36

97.91 ± 9.96

97.54 ± 9.96

99.69 ± 9.99

99.00 ± 8.77

99.17 ± 9.17

98.86 ± 9.12

101.35 ± 7.12

100.18 ± 6.83

100.03 ± 6.57

99.98 ± 6.72

HC

104.73 ± 9.41

105.03 ± 9.70

104.24 ± 9.99

105.07 ± 9.62

102.03 ± 12.00

100.60 ± 14.22

100.09 ± 13.79

104.35 ± 9.26

104.95 ± 9.96

105.05 ± 14.22

103.81 ± 9.93

104.06 ± 10.05

105.20 ± 11.74

105.14 ± 11.77

104.99 ± 11.57

104.39 ± 11.50

107.33 ± 10.59

106.34 ± 11.35

105.08 ± 11.44

105.23 ± 11.56

Cadence CV [steps/min]

PwCA

0.03 ± 0.02

0.02 ± 0.01

0.04 ± 0.02

0.02 ± 0.014

0.03 ± 0.02

0.23 ± 0.01

0.03 ± 0.02

0.03 ± 0.02

0.03 ± 0.01

0.02 ± 0.01

0.02 ± 0.01

0.02 ± 0.01

0.03 ± 0.01

0.03 ± 0.02

0.03 ± 0.02

0.03 ± 0.02

0.02 ± 0.01

0.02 ± 0.01

0.02 ± 0.02

0.02 ± 0.01

HC

0.02 ± 0.02

0.01 ± 0.00

0.23 ± 0.03

0.01 ± 0.00

0.03 ± 0.02

0.03 ± 0.02

0.04 ± 0.03

0.03 ± 0.02

0.02 ± 0.01

0.01 ± 0.00

0.16 ± 0.01

0.12 ± 0.01

0.03 ± 0.02

0.02 ± 0.01

0.03 ± 0.02

0.3 ± 0.03

0.02 ± 0.01

0.01 ± 0.00

0.01 ± 0.00

0.01 ± 0.00

Stride length mean [meters]

PwCA

1.11 ± 0.14

1.11 ± 1.14

1.08 ± 0.12

1.09 ± 0.13

1.06 ± 0.15

1.06 ± 0.16

1.03 ± 0.16

1.03 ± 0.15

1.10 ± 0.14

1.10 ± 0.15

1.10 ± 0.14

1.11 ± 0.14

1.04 ± 0.18

1.04 ± 0.17

1.03 ± 0.18

1.03 ± 0.19

1.11 ± 0.13

1.10 ± 0.13

1.10 ± 0.15

1.10 ± 0.15

HC

1.17 ± 0.18

1.17 ± 0.18

1.17 ± 0.17

1.17 ± 0.17

1.19 ± 0.19

1.18 ± 0.19

1.16 ± 0.21

1.17 ± 0.20

1.21 ± 0.16

1.20 ± 0.15

1.17 ± 0.17

1.18 ± 0.17

1.21 ± 0.21

1.16 ± 0.21

1.14 ± 0.21

1.13 ± 0.20

1.22 ± 0.15

1.22 ± 0.16

1.23 ± 0.16

1.24 ± 0.16

Stride length CV [meters]

PwCA

0.04 ± 0.01

0.03 ± 0.01

0.04 ± 0.01

0.04 ± 0.01

0.06 ± 0.03

0.04 ± 0.02

0.05 ± 0.03

0.05 ± 0.02

0.04 ± 0.01

0.04 ± 0.02

0.04 ± 0.02

0.03 ± 0.01

0.06 ± 0.04

0.05 ± 0.02

0.05 ± 0.02

0.05 ± 0.02

0.03 ± 0.02

0.03 ± 0.02

0.04 ± 0.02

0.04 ± 0.02

HC

0.04 ± 0.03

0.03 ± 0.01

0.03 ± 0.02

0.03 ± 0.01

0.04 ± 0.01

0.03 ± 0.01

0.04 ± 0.03

0.04 ± 0.02

0.03 ± 0.02

0.03 ± 0.01

0.43 ± 0.02

0.03 ± 0.02

0.04 ± 0.02

0.04 ± 0.01

0.04 ± 0.02

0.04 ± 0.02

0.03 ± 0.01

0.02 ± 0.00

0.02 ± 0.01

0.02 ± 0.01

Speed mean [meters/second]

PwCA

0.92 ± 0.18

0.92 ± 0.17

0.86 ± 0.12

0.86 ± 0.13

0.86 ± 0.16

0.87 ± 0.16

0.83 ± 0.18

0.82 ± 0.17

0.92 ± 0.19

0.92 ± 0.20

0.91 ± 0.18

0.91 ± 0.18

0.87 ± 0.19

0.86 ± 1.18

0.86 ± 0.18

0.86 ± 0.19

0.94 ± 0.15

0.92 ± 0.14

0.92 ± 0.15

0.92 ± 0.17

HC

1.03 ± 1.20

1.02 ± 0.19

1.02 ± 0.20

1.03 ± 0.19

1.03 ± 0.26

1.00 ± 0.27

0.98 ± 0.28

1.03 ± 0.23

1.06 ± 0.20

1.05 ± 0.19

1.02 ± 0.18

1.02 ± 0.19

1.07 ± 0.27

1.03 ± 0.26

1.00 ± 0.25

0.99 ± 0.24

1.10 ± 0.24

1.09 ± 0.25

1.09 ± 0.24

1.10 ± 0.24

Speed CV [meters/second]

PwCA

0.05 ± 0.02

0.04 ± 0.02

0.07 ± 0.03

0.05 ± 0.02

0.07 ± 0.03

0.06 ± 0.02

0.06 ± 0.03

0.06 ± 0.03

0.05 ± 0.02

0.04 ± 0.02

0.04 ± 0.02

0.04 ± 0.01

0.07 ± 0.05

0.06 ± 0.03

0.06 ± 0.03

0.06 ± 0.03

0.05 ± 0.02

0.05 ± 0.02

0.05 ± 0.04

0.05 ± 0.03

HC

0.05 ± 0.02

0.03 ± 0.01

0.04 ± 0.03

0.03 ± 0.01

0.05 ± 0.03

0.04 ± 0.02

0.06 ± 0.04

0.05 ± 0.02

0.04 ± 0.02

0.03 ± 0.01

0.04 ± 0.02

0.03 ± 0.01

0.05 ± 0.02

0.05 ± 0.02

0.05 ± 0.02

0.06 ± 0.03

0.04 ± 0.01

0.03 ± 0.01

0.03 ± 0.01

0.02 ± 0.01

Double support mean [% Gait Cycle Time]

PwCA

24.58 ± 3.68

24.93 ± 3.38

25. 62 ± 3.37

25.67 ± 3.59

25.45 ± 4.73

25.62 ± 4.28

26.47 ± 4.55

26.62 ± 4.05

24.46 ± 3.66

24. 74 ± 3.48

25.09 ± 3.54

2512 ± 3.37

25.64 ± 2.84

25.87 ± 3.70

25.94 ± 2.87

25.97 ± 2.84

25.10 ± 2.93

25.44 ± 2.89

25.46 ± 2.99

25.52 ± 3.17

HC

22.00 ± 2.47

22.26 ± 3.33

22.27 ± 2.29

22.23 ± 3.52

21.11 ± 4.55

21.60 ± 4.39

22.45 ± 4.76

21.90 ± 4.27

21.79 ± 3.37

21.99 ± 3.43

22.41 ± 3.42

22.66 ± 3.23

20.76 ± 4.02

21.59 ± 4.37

21.94 ± 4.66

21.80 ± 4.63

21.47 ± 3.96

21.78 ± 4.10

22.03 ± 4.05

21.89 ± 4.01

Double support CV [% Gait Cycle Time]

PwCA

0.06 ± 0.02

0.05 ± 0.02

0.06 ± 0.02

0.05 ± 0.02

0.07 ± 0.03

0.06 ± 0.03

0.06 ± 0.03

0.06 ± 0.02

0.06 ± 0.04

0.05 ± 0.03

0.05 ± 0.02

0.05 ± 0.01

0.06 ± 0.03

0.06 ± 0.02

0.06 ± 0.03

0.07 ± 0.03

0.05 ± 0.01

0.05 ± 0.01

0.05 ± 0.01

0.05 ± 0.02

HC

0.05 ± 0.02

0.04 ± 0.01

0.05 ± 0.02

0.05 ± 0.01

0.06 ± 0.03

0.06 ± 0.03

0.07 ± 0.03

0.06 ± 0.03

0.05 ± 0.02

0.04 ± 0.01

0.05 ± 0.02

0.04 ± 0.01

0.07 ± 0.02

0.06 ± 0.02

0.06 ± 0.03

0.07 ± 0.03

0.05 ± 0.02

0.04 ± 0.01

0.04 ± 0.01

0.04 ± 0.01

Step duration mean [seconds]

PwCA

0.61 ± 0.06

0.62 ± 0.06

0.64 ± 0.05

0.64 ± 0.06

0.62 ± 0.06

0.62 ± 0.05

0.63 ± 0.06

0.64 ± 0.07

0.62 ± 0.07

0.62 ± 0.07

0.62 ± 0.07

0.62 ± 0.07

0.61 ± 0.07

0.61 ± 0.06

0.61 ± 0.06

0.61 ± 0.06

0.60 ± 0.04

0.60 ± 0.04

0.60 ±0.04

0.60 ± 0.04

HC

0.58 ± 0.05

0.58 ± 0.05

0.58 ± 0.06

0.58 ± 0.05

0.60 ± 0.07

0.61 ± 0.10

0.61 ± 0.09

0.58 ± 0.05

0.58 ± 0.06

0.58 ± 0.06

0.58 ± 0.06

0.58 ± 0.06

0.58 ± 0.07

0.58 ± 0.07

0.58 ± 0.06

0.58 ± 0.06

0.56 ± 0.06

0.57 ± 0.06

0.58 ± 0.06

0.58 ± 0.06

Step duration CV [seconds]

PwCA

0.04 ± 0.02

0.04 ± 0.02

0.05 ± 0.02

0.04 ± 0.02

0.04 ± 0.02

0.04 ± 0.02

0.04 ± 0.02

0.04 ± 0.02

0.04 ± 0.02

0.03 ± 0.02

0.03 ± 0.01

0.03 ± 0.01

0.04 ± 0.02

0.05 ± 0.02

0.04 ± 0.02

0.04 ± 0.03

0.03 ± 0.01

0.03 ± 0.01

0.04 ± 0.02

0.03 ± 0.02

HC

0.03 ± 0.02

0.02 ± 0.01

0.03 ± 0.03

0.02 ± 0.01

0.04 ± 0.02

0.04 ± 0.02

0.05 ± 0.03

0.04 ± 0.02

0.03 ± 0.01

0.02 ± 0.01

0.03 ± 0.01

0.02 ± 0.01

0.04 ± 0.02

0.04 ± 0.02

0.04 ± 0.02

0.05 ± 0.03

0.03 ± 0.01

0.02 ± 0.01

0.02 ± 0.01

0.02 ± 0.01