Table 6. Summary of results from experimental session three, presented as mean and standard deviations for each outcome measure, across groups (cerebellar patients and controls), stimuli (music and metronome) and conditions (Adaptive, Non-Adaptive, Silence). PwCA: persons with cerebellar ataxia; HC: healthy controls, Min: minutes.
Outcome measures | Group | Adaptive metronome condition | Adaptive music condition | Non-adaptive metronome condition | Non-Adaptive music condition | Silence condition | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Min 1-2 | Min 3-4 | Min 5-6 | Min 7-8 | Min 1-2 | Min 3-4 | Min 5-6 | Min 7-8 | Min 1-2 | Min 3-4 | Min 5-6 | Min 7-8 | Min 1-2 | Min 3-4 | Min 5-6 | Min 7-8 | Min 1-2 | Min 3-4 | Min 5-6 | Min 7-8 | ||
Resultant Vector Length [0-1] | PwCA | 0.86 ± 0.20 | 0.85 ± 0.20 | 0.80 ± 0.21 | 0.80 ± 0.23 | 0.80 ± 0.20 | 0.81 ± 0.17 | 0.81 ± 0.23 | 0.79 ± 0.20 | 0.69 ± 0.29 | 0.75 ± 0.31 | 0.68 ± 0.33 | 0.64 ± 0.32 | 0.61 ± 0.33 | 0.60 ± 0.31 | 0.69 ± 0.31 | 0.63 ± 0.29 | - | |||
HC | 0.94 ± 0.04 | 0.96 ± 0.02 | 0.94 ± 0.05 | 0.96 ± 0.04 | 0.91 ± 0.07 | 0.88 ± 0.013 | 0.82 ± 0.18 | 0.87 ± 0.12 | 0.90 ± 0.06 | 0.92 ± 0.07 | 0.87 ± 0.14 | 0.81 ± 0.26 | 0.74 ± 0.25 | 0.77 ± 0.19 | 0.75 ± 0.26 | 0.65 ± 0.30 | - | ||||
Relative Phase Angle [degrees] | PwCA | -38.15 ± 30.85 | -31.13 ± 50.68 | -21.53 ± 55.89 | -34.24 ± 66.79 | -24.28 ± 49.41 | -12.39 ± 33.59 | -12.93 ± 42.08 | -10.64 ± 40.68 | -44.45 ± 43.23 | -50.28 ± 43.32 | -18.65 ± 27.35 | -36.56 ± 57.14 | -8.47 ± 47.51 | 1.72 ± 64.16 - | -8.33 ± 60.56 | 23.08 ± 55.08 - | - | |||
HC | -36.81 ± 19.08 | -28.56 ± 18.85 | -26.01 ± 22.76 | -30.56 ± 24.48 | -10.86 ± 45.38 | 2.68 ± 36.37 | -2.48 ± 55.73 | -16.11 ± 50.94 | -45.03 ± 32.61 | -34.44 ± 30.57 | -36.23 ± 39.87 | -38.70 ± 48.90 | -20.06 ± 49.25 | -19.42 ± 36.73 | -6.74 ± 31.87 | -6.05 ± 32.15 | - | ||||
Alpha [0-1] | PwCA | 0.83 ± 0.28 | 0.83 ± 0.28 | 0.49 ± 0.25 | 0.65 ± 0.27 | 0.80 ± 0.16 | |||||||||||||||
HC | 0.62 ± 0.21 | 0.88 ± 0.30 | 0.33 ± 0.25 | 0.70 ± 0.27 | 0.84 ± 0.25 | ||||||||||||||||
Cadence mean [steps/min] | PwCA | 98.81 ± 9.51 | 98.19 ± 9.58 | 95.07 ± 7.01 | 94.69 ± 8,59 | 97.25 ± 8.66 | 97.92 ± 7.78 | 95.88 ± 9.18 | 94.65 ± 9.711 | 98.60 ± 10.43 | 98.15 ± 10.36 | 97.91 ± 9.96 | 97.54 ± 9.96 | 99.69 ± 9.99 | 99.00 ± 8.77 | 99.17 ± 9.17 | 98.86 ± 9.12 | 101.35 ± 7.12 | 100.18 ± 6.83 | 100.03 ± 6.57 | 99.98 ± 6.72 |
HC | 104.73 ± 9.41 | 105.03 ± 9.70 | 104.24 ± 9.99 | 105.07 ± 9.62 | 102.03 ± 12.00 | 100.60 ± 14.22 | 100.09 ± 13.79 | 104.35 ± 9.26 | 104.95 ± 9.96 | 105.05 ± 14.22 | 103.81 ± 9.93 | 104.06 ± 10.05 | 105.20 ± 11.74 | 105.14 ± 11.77 | 104.99 ± 11.57 | 104.39 ± 11.50 | 107.33 ± 10.59 | 106.34 ± 11.35 | 105.08 ± 11.44 | 105.23 ± 11.56 | |
Cadence CV [steps/min] | PwCA | 0.03 ± 0.02 | 0.02 ± 0.01 | 0.04 ± 0.02 | 0.02 ± 0.014 | 0.03 ± 0.02 | 0.23 ± 0.01 | 0.03 ± 0.02 | 0.03 ± 0.02 | 0.03 ± 0.01 | 0.02 ± 0.01 | 0.02 ± 0.01 | 0.02 ± 0.01 | 0.03 ± 0.01 | 0.03 ± 0.02 | 0.03 ± 0.02 | 0.03 ± 0.02 | 0.02 ± 0.01 | 0.02 ± 0.01 | 0.02 ± 0.02 | 0.02 ± 0.01 |
HC | 0.02 ± 0.02 | 0.01 ± 0.00 | 0.23 ± 0.03 | 0.01 ± 0.00 | 0.03 ± 0.02 | 0.03 ± 0.02 | 0.04 ± 0.03 | 0.03 ± 0.02 | 0.02 ± 0.01 | 0.01 ± 0.00 | 0.16 ± 0.01 | 0.12 ± 0.01 | 0.03 ± 0.02 | 0.02 ± 0.01 | 0.03 ± 0.02 | 0.3 ± 0.03 | 0.02 ± 0.01 | 0.01 ± 0.00 | 0.01 ± 0.00 | 0.01 ± 0.00 | |
Stride length mean [meters] | PwCA | 1.11 ± 0.14 | 1.11 ± 1.14 | 1.08 ± 0.12 | 1.09 ± 0.13 | 1.06 ± 0.15 | 1.06 ± 0.16 | 1.03 ± 0.16 | 1.03 ± 0.15 | 1.10 ± 0.14 | 1.10 ± 0.15 | 1.10 ± 0.14 | 1.11 ± 0.14 | 1.04 ± 0.18 | 1.04 ± 0.17 | 1.03 ± 0.18 | 1.03 ± 0.19 | 1.11 ± 0.13 | 1.10 ± 0.13 | 1.10 ± 0.15 | 1.10 ± 0.15 |
HC | 1.17 ± 0.18 | 1.17 ± 0.18 | 1.17 ± 0.17 | 1.17 ± 0.17 | 1.19 ± 0.19 | 1.18 ± 0.19 | 1.16 ± 0.21 | 1.17 ± 0.20 | 1.21 ± 0.16 | 1.20 ± 0.15 | 1.17 ± 0.17 | 1.18 ± 0.17 | 1.21 ± 0.21 | 1.16 ± 0.21 | 1.14 ± 0.21 | 1.13 ± 0.20 | 1.22 ± 0.15 | 1.22 ± 0.16 | 1.23 ± 0.16 | 1.24 ± 0.16 | |
Stride length CV [meters] | PwCA | 0.04 ± 0.01 | 0.03 ± 0.01 | 0.04 ± 0.01 | 0.04 ± 0.01 | 0.06 ± 0.03 | 0.04 ± 0.02 | 0.05 ± 0.03 | 0.05 ± 0.02 | 0.04 ± 0.01 | 0.04 ± 0.02 | 0.04 ± 0.02 | 0.03 ± 0.01 | 0.06 ± 0.04 | 0.05 ± 0.02 | 0.05 ± 0.02 | 0.05 ± 0.02 | 0.03 ± 0.02 | 0.03 ± 0.02 | 0.04 ± 0.02 | 0.04 ± 0.02 |
HC | 0.04 ± 0.03 | 0.03 ± 0.01 | 0.03 ± 0.02 | 0.03 ± 0.01 | 0.04 ± 0.01 | 0.03 ± 0.01 | 0.04 ± 0.03 | 0.04 ± 0.02 | 0.03 ± 0.02 | 0.03 ± 0.01 | 0.43 ± 0.02 | 0.03 ± 0.02 | 0.04 ± 0.02 | 0.04 ± 0.01 | 0.04 ± 0.02 | 0.04 ± 0.02 | 0.03 ± 0.01 | 0.02 ± 0.00 | 0.02 ± 0.01 | 0.02 ± 0.01 | |
Speed mean [meters/second] | PwCA | 0.92 ± 0.18 | 0.92 ± 0.17 | 0.86 ± 0.12 | 0.86 ± 0.13 | 0.86 ± 0.16 | 0.87 ± 0.16 | 0.83 ± 0.18 | 0.82 ± 0.17 | 0.92 ± 0.19 | 0.92 ± 0.20 | 0.91 ± 0.18 | 0.91 ± 0.18 | 0.87 ± 0.19 | 0.86 ± 1.18 | 0.86 ± 0.18 | 0.86 ± 0.19 | 0.94 ± 0.15 | 0.92 ± 0.14 | 0.92 ± 0.15 | 0.92 ± 0.17 |
HC | 1.03 ± 1.20 | 1.02 ± 0.19 | 1.02 ± 0.20 | 1.03 ± 0.19 | 1.03 ± 0.26 | 1.00 ± 0.27 | 0.98 ± 0.28 | 1.03 ± 0.23 | 1.06 ± 0.20 | 1.05 ± 0.19 | 1.02 ± 0.18 | 1.02 ± 0.19 | 1.07 ± 0.27 | 1.03 ± 0.26 | 1.00 ± 0.25 | 0.99 ± 0.24 | 1.10 ± 0.24 | 1.09 ± 0.25 | 1.09 ± 0.24 | 1.10 ± 0.24 | |
Speed CV [meters/second] | PwCA | 0.05 ± 0.02 | 0.04 ± 0.02 | 0.07 ± 0.03 | 0.05 ± 0.02 | 0.07 ± 0.03 | 0.06 ± 0.02 | 0.06 ± 0.03 | 0.06 ± 0.03 | 0.05 ± 0.02 | 0.04 ± 0.02 | 0.04 ± 0.02 | 0.04 ± 0.01 | 0.07 ± 0.05 | 0.06 ± 0.03 | 0.06 ± 0.03 | 0.06 ± 0.03 | 0.05 ± 0.02 | 0.05 ± 0.02 | 0.05 ± 0.04 | 0.05 ± 0.03 |
HC | 0.05 ± 0.02 | 0.03 ± 0.01 | 0.04 ± 0.03 | 0.03 ± 0.01 | 0.05 ± 0.03 | 0.04 ± 0.02 | 0.06 ± 0.04 | 0.05 ± 0.02 | 0.04 ± 0.02 | 0.03 ± 0.01 | 0.04 ± 0.02 | 0.03 ± 0.01 | 0.05 ± 0.02 | 0.05 ± 0.02 | 0.05 ± 0.02 | 0.06 ± 0.03 | 0.04 ± 0.01 | 0.03 ± 0.01 | 0.03 ± 0.01 | 0.02 ± 0.01 | |
Double support mean [% Gait Cycle Time] | PwCA | 24.58 ± 3.68 | 24.93 ± 3.38 | 25. 62 ± 3.37 | 25.67 ± 3.59 | 25.45 ± 4.73 | 25.62 ± 4.28 | 26.47 ± 4.55 | 26.62 ± 4.05 | 24.46 ± 3.66 | 24. 74 ± 3.48 | 25.09 ± 3.54 | 2512 ± 3.37 | 25.64 ± 2.84 | 25.87 ± 3.70 | 25.94 ± 2.87 | 25.97 ± 2.84 | 25.10 ± 2.93 | 25.44 ± 2.89 | 25.46 ± 2.99 | 25.52 ± 3.17 |
HC | 22.00 ± 2.47 | 22.26 ± 3.33 | 22.27 ± 2.29 | 22.23 ± 3.52 | 21.11 ± 4.55 | 21.60 ± 4.39 | 22.45 ± 4.76 | 21.90 ± 4.27 | 21.79 ± 3.37 | 21.99 ± 3.43 | 22.41 ± 3.42 | 22.66 ± 3.23 | 20.76 ± 4.02 | 21.59 ± 4.37 | 21.94 ± 4.66 | 21.80 ± 4.63 | 21.47 ± 3.96 | 21.78 ± 4.10 | 22.03 ± 4.05 | 21.89 ± 4.01 | |
Double support CV [% Gait Cycle Time] | PwCA | 0.06 ± 0.02 | 0.05 ± 0.02 | 0.06 ± 0.02 | 0.05 ± 0.02 | 0.07 ± 0.03 | 0.06 ± 0.03 | 0.06 ± 0.03 | 0.06 ± 0.02 | 0.06 ± 0.04 | 0.05 ± 0.03 | 0.05 ± 0.02 | 0.05 ± 0.01 | 0.06 ± 0.03 | 0.06 ± 0.02 | 0.06 ± 0.03 | 0.07 ± 0.03 | 0.05 ± 0.01 | 0.05 ± 0.01 | 0.05 ± 0.01 | 0.05 ± 0.02 |
HC | 0.05 ± 0.02 | 0.04 ± 0.01 | 0.05 ± 0.02 | 0.05 ± 0.01 | 0.06 ± 0.03 | 0.06 ± 0.03 | 0.07 ± 0.03 | 0.06 ± 0.03 | 0.05 ± 0.02 | 0.04 ± 0.01 | 0.05 ± 0.02 | 0.04 ± 0.01 | 0.07 ± 0.02 | 0.06 ± 0.02 | 0.06 ± 0.03 | 0.07 ± 0.03 | 0.05 ± 0.02 | 0.04 ± 0.01 | 0.04 ± 0.01 | 0.04 ± 0.01 | |
Step duration mean [seconds] | PwCA | 0.61 ± 0.06 | 0.62 ± 0.06 | 0.64 ± 0.05 | 0.64 ± 0.06 | 0.62 ± 0.06 | 0.62 ± 0.05 | 0.63 ± 0.06 | 0.64 ± 0.07 | 0.62 ± 0.07 | 0.62 ± 0.07 | 0.62 ± 0.07 | 0.62 ± 0.07 | 0.61 ± 0.07 | 0.61 ± 0.06 | 0.61 ± 0.06 | 0.61 ± 0.06 | 0.60 ± 0.04 | 0.60 ± 0.04 | 0.60 ±0.04 | 0.60 ± 0.04 |
HC | 0.58 ± 0.05 | 0.58 ± 0.05 | 0.58 ± 0.06 | 0.58 ± 0.05 | 0.60 ± 0.07 | 0.61 ± 0.10 | 0.61 ± 0.09 | 0.58 ± 0.05 | 0.58 ± 0.06 | 0.58 ± 0.06 | 0.58 ± 0.06 | 0.58 ± 0.06 | 0.58 ± 0.07 | 0.58 ± 0.07 | 0.58 ± 0.06 | 0.58 ± 0.06 | 0.56 ± 0.06 | 0.57 ± 0.06 | 0.58 ± 0.06 | 0.58 ± 0.06 | |
Step duration CV [seconds] | PwCA | 0.04 ± 0.02 | 0.04 ± 0.02 | 0.05 ± 0.02 | 0.04 ± 0.02 | 0.04 ± 0.02 | 0.04 ± 0.02 | 0.04 ± 0.02 | 0.04 ± 0.02 | 0.04 ± 0.02 | 0.03 ± 0.02 | 0.03 ± 0.01 | 0.03 ± 0.01 | 0.04 ± 0.02 | 0.05 ± 0.02 | 0.04 ± 0.02 | 0.04 ± 0.03 | 0.03 ± 0.01 | 0.03 ± 0.01 | 0.04 ± 0.02 | 0.03 ± 0.02 |
HC | 0.03 ± 0.02 | 0.02 ± 0.01 | 0.03 ± 0.03 | 0.02 ± 0.01 | 0.04 ± 0.02 | 0.04 ± 0.02 | 0.05 ± 0.03 | 0.04 ± 0.02 | 0.03 ± 0.01 | 0.02 ± 0.01 | 0.03 ± 0.01 | 0.02 ± 0.01 | 0.04 ± 0.02 | 0.04 ± 0.02 | 0.04 ± 0.02 | 0.05 ± 0.03 | 0.03 ± 0.01 | 0.02 ± 0.01 | 0.02 ± 0.01 | 0.02 ± 0.01 | |