Fig. 11
Mechanism of phage in biofilm disturbance using depolymerase, quorum sensing inhibition and tail-specific protein binding on biofilm bacteria; phage tail protein is like a lock and key model, which specifically binds to its host organism for infection and production of prophage; Depolymerase (holin) is a specific enzyme produced by phage for initiation of host infection and insertion of genetic material inside the host cell; The size of the phage is nanoscale, it was easy to penetrate the biofilm of bacteria to kill their host present inside the biofilm.
