Fig. 4
From: An improved synthesis of TRβ-selective thyromimetic GC-1
Modified synthetic route for GC-1. Reaction condition: i) BnBr, NaH, DMF, Bu4NF, CH2Cl2,24 h; Acetone, ii) Cs2CO3, DMF, BrCH2COOBn, 2 h; iii) 10%Pd/C, H2, MeOH, AcOH, MnO2, Bu4NF, CH2Cl2.
