Fig. 2
From: IGF-1R promotes pain-like behavior in rats with myofascial pain syndrome via the PI3K/AKT pathway
IGF-1 and IGF-1R expression was increased in MTrPs group. (A) IGF-1 and IGF-1R was detected in gastrocnemius muscle tissue (The arrows indicate expression of IGF-1 and IGF-1R.). The mean optical densities of IGF-1 and IGF-1R were significantly higher in MTrPs group compared to control group (**P < 0.01). The data expressed as mean ± standard deviation (mean ± SD). (B) IGF-1 and IGF-1R protein was analyzed by Western blot. The fold changes of IGF-1 and IGF-1R were remarkedly higher in MTrPs group than that in control group (**P < 0.01). The data expressed as mean ± standard deviation (mean ± SD).
