Fig. 3 | Scientific Reports

Fig. 3

From: Exploration of common pathogenic genes between cerebral amyloid angiopathy and insomnia based on bioinformatics and experimental validation

Fig. 3The alternative text for this image may have been generated using AI.

Identification of hub genes using PPI network and machine learning. (A) Construction of the PPI network. (B) Identification of core genes using multiple PPI algorithms. (C) Selection of hub genes in the CAA dataset using XGBoost and RF models. (D) Selection of hub genes in the insomnia dataset using XGBoost and RF models. (E) Expression validation of hub genes in both the insomnia and CAA datasets. (F) ROC curve analysis of hub genes. (G) Correlation analysis between POLR1B and CBX5.

Back to article page