Fig. 2
From: The P4HB/LGALS3BP/NF-kB axis promotes the progression of MIA to IAC in lung adenocarcinoma
P4HB inhibited ferroptosis in LUAD cells. (A) Analysis of the GSE189357 dataset to find differences in ferroptosis levels in MIA and IAC. Detection of the effect of P4HB on (B) ROS and (C) JC-1 levels in LUAD cells after treatment with the ferroptosis inducer erastin. (D, E) Detection of ferroptosis markers MDA and GSH in cell lines transfected with P4HB plasmid and empty plasmid. P4HB, transfected with P4HB plasmid; NC, transfected with empty plasmid. All data represent mean ± SD of four independent experiments. *, P < 0.05; **, P < 0.01; ***, P < 0.001.
