Table 1 Weighted baseline characteristics of the study population based on Non-HDL-C/HDL-C ratio.
Variables | Non-HDL-C/HDL-C ratio (NHHR) | p-value | ||||
|---|---|---|---|---|---|---|
Overall Weighted N = 140,351,693 Unweighted n = 18,283 | Q1 Weighted N = 35,408,346 Unweighted n = 4,570 | Q2 Weighted N = 34,863,849 Unweighted n = 4,571 | Q3 Weighted N = 34,824,667 Unweighted n = 4,570 | Q4 Weighted N = 35,254,831 Unweighted n = 4,572 | ||
Age, Median (Q1, Q3) | 51 (39, 62) | 51 (37, 65) | 52 (39, 63) | 51 (40, 61) | 49 (39, 59) | < 0.001 |
Gender, n(%) | < 0.001 | |||||
Female | 70,459,970 (50.20%) | 23,446,266 (66.22%) | 19,968,427 (57.28%) | 15,034,197 (43.17%) | 12,011,080 (34.07%) | |
Male | 69,891,722 (49.80%) | 11,962,080 (33.78%) | 14,895,422 (42.72%) | 19,790,470 (56.83%) | 23,243,750 (65.93%) | |
Race, n(%) | < 0.001 | |||||
Mexican American | 10,680,191 (7.61%) | 1,778,426 (5.02%) | 2,228,910 (6.39%) | 3,051,201 (8.76%) | 3,621,654 (10.27%) | |
Other Hispanic | 6,632,736 (4.73%) | 1,221,070 (3.45%) | 1,565,648 (4.49%) | 1,848,489 (5.31%) | 1,997,528 (5.67%) | |
Non-Hispanic White | 100,464,233 (71.58%) | 25,669,345 (72.50%) | 25,162,261 (72.17%) | 24,533,233 (70.45%) | 25,099,394 (71.19%) | |
Non-Hispanic Black | 13,504,251 (9.62%) | 4,494,317 (12.69%) | 3,595,249 (10.31%) | 3,165,383 (9.09%) | 2,249,302 (6.38%) | |
Other Race | 9,070,282 (6.46%) | 2,245,188 (6.34%) | 2,311,781 (6.63%) | 2,226,360 (6.39%) | 2,286,953 (6.49%) | |
Education, n(%) | < 0.001 | |||||
Less Than 9th Grade | 7,895,288 (5.63%) | 1,380,737 (3.90%) | 1,739,728 (4.99%) | 2,111,154 (6.06%) | 2,663,670 (7.56%) | |
9-12th Grade | 15,319,986 (10.92%) | 3,314,299 (9.36%) | 3,251,359 (9.33%) | 4,202,845 (12.07%) | 4,551,484 (12.91%) | |
High School Grade | 33,838,805 (24.11%) | 7,582,749 (21.42%) | 7,820,526 (22.43%) | 8,931,817 (25.65%) | 9,503,713 (26.96%) | |
AA degree | 42,476,945 (30.26%) | 10,527,290 (29.73%) | 10,950,732 (31.41%) | 10,134,001 (29.10%) | 10,864,923 (30.82%) | |
College graduate or above | 40,717,701 (29.01%) | 12,565,986 (35.49%) | 11,091,234 (31.81%) | 9,444,312 (27.12%) | 7,616,169 (21.60%) | |
Other grade | 102,967 (0.07%) | 37,285 (0.11%) | 10,271 (0.03%) | 538 (0.00%) | 54,872 (0.16%) | |
Body mass index, Median (Q1, Q3) | 27.4 (24.0, 31.4) | 24.4 (21.9, 28.1) | 26.9 (23.8, 31.0) | 28.3 (25.2, 32.2) | 29.7 (26.7, 33.2) | < 0.001 |
Hypertension, n(%) | < 0.001 | |||||
No | 89,552,977 (63.81%) | 24,061,495 (67.95%) | 22,486,366 (64.50%) | 21,492,247 (61.72%) | 21,512,869 (61.02%) | |
Yes | 50,798,715 (36.19%) | 11,346,851 (32.05%) | 12,377,483 (35.50%) | 13,332,419 (38.28%) | 13,741,962 (38.98%) | |
Glomerular Filtration Rate | 74 (64, 84) | 76 (65, 87) | 75 (64, 85) | 74 (63, 83) | 73 (63, 83) | < 0.001 |
Chronic kidney disease, n(%) | 0.019 | |||||
No | 112,875,330 (80.42%) | 29,095,813 (82.17%) | 28,075,434 (80.53%) | 27,729,486 (79.63%) | 27,974,597 (79.35%) | |
Yes | 27,476,363 (19.58%) | 6,312,533 (17.83%) | 6,788,415 (19.47%) | 7,095,181 (20.37%) | 7,280,234 (20.65%) | |
Diabetes, n(%) | < 0.001 | |||||
No | 123,350,873 (87.89%) | 31,739,887 (89.64%) | 30,786,494 (88.30%) | 30,463,736 (87.48%) | 30,360,756 (86.12%) | |
Yes | 17,000,820 (12.11%) | 3,668,460 (10.36%) | 4,077,355 (11.70%) | 4,360,930 (12.52%) | 4,894,075 (13.88%) | |
Smoking, n(%) | < 0.001 | |||||
No | 74,402,118 (53.01%) | 19,741,162 (55.75%) | 19,175,401 (55.00%) | 18,544,300 (53.25%) | 16,941,254 (48.05%) | |
Yes | 65,949,575 (46.99%) | 15,667,184 (44.25%) | 15,688,448 (45.00%) | 16,280,367 (46.75%) | 18,313,577 (51.95%) | |
Femur neck BMD, (mg/dL) | 0.81 (0.72, 0.92) | 0.77 (0.68, 0.88) | 0.80 (0.71, 0.91) | 0.83 (0.73, 0.93) | 0.84 (0.75, 0.94) | < 0.001 |
Trochanter BMD, (mg/dL) | 0.72 (0.64, 0.81) | 0.68 (0.61, 0.77) | 0.72 (0.63, 0.80) | 0.73 (0.65, 0.83) | 0.76 (0.67, 0.84) | < 0.001 |
Intertrochanter BMD, (mg/dL) | 1.14 (1.02, 1.26) | 1.08 (0.96, 1.20) | 1.13 (1.00, 1.25) | 1.16 (1.04, 1.28) | 1.19 (1.07, 1.31) | < 0.001 |
Total femur BMD, (mg/dL) | 0.96 (0.86, 1.07) | 0.91 (0.81, 1.01) | 0.95 (0.84, 1.05) | 0.98 (0.87, 1.08) | 1.01 (0.91, 1.10) | < 0.001 |
Osteopenia, n(%) | < 0.001 | |||||
No | 67,952,909 (48.42%) | 14,737,131 (41.62%) | 16,351,496 (46.90%) | 17,741,333 (50.94%) | 19,122,948 (54.24%) | |
Yes | 72,398,784 (51.58%) | 20,671,215 (58.38%) | 18,512,353 (53.10%) | 17,083,334 (49.06%) | 16,131,883 (45.76%) | |
Osteoporosis, n(%) | < 0.001 | |||||
No | 134,269,627 (95.67%) | 33,197,868 (93.76%) | 33,188,087 (95.19%) | 33,470,247 (96.11%) | 34,413,426 (97.61%) | |
Yes | 6,082,066 (4.33%) | 2,210,478 (6.24%) | 1,675,762 (4.81%) | 1,354,420 (3.89%) | 841,405 (2.39%) | |
Low bone mass, n(%) | < 0.001 | |||||
No | 67,169,149 (47.86%) | 14,348,854 (40.52%) | 16,188,750 (46.43%) | 17,589,890 (50.51%) | 19,041,654 (54.01%) | |
Yes | 73,182,544 (52.14%) | 21,059,492 (59.48%) | 18,675,099 (53.57%) | 17,234,776 (49.49%) | 16,213,177 (45.99%) | |
