Table 1 Comparison of demographic and clinical characteristics of NHANES participants with and without elevated serum high-sensitivity CRP (> 3.0 mg/L).
Variables | Overall (N = 6358) | Control (≤ 3.0 mg/L) (n = 4144) | Elevated serum CRP (> 3.0 mg/L) (n = 2214) | P |
|---|---|---|---|---|
Sex | < 0.001 | |||
Female | 3245 (50.3%) | 1926 (46.3%) | 1319 (58.5%) | |
Male | 3113 (49.7%) | 2218 (53.7%) | 895 (41.5%) | |
Age (years) | 49.3 ± 12.8 | 49.6 ± 13.1 | 48.9 ± 12.3 | 0.415 |
Race | < 0.001 | |||
Non-Hispanic White | 1993 (63.8%) | 1325 (65.1%) | 668 (61.0%) | |
Non-Hispanic Black | 1488 (10.3%) | 865 (8.9%) | 623 (13.3%) | |
Mexican American | 976 (8.8%) | 609 (8.4%) | 367 (9.7%) | |
Other | 1901 (17.0%) | 1345 (17.5%) | 556 (16.0%) | |
Education | < 0.001 | |||
< High school | 1286 (12.1%) | 823 (12.1%) | 463 (12.2%) | |
High school | 1343 (21.3%) | 816 (19.2%) | 527 (25.5%) | |
> High school | 3725 (66.6%) | 2503 (68.6%) | 1222 (62.3%) | |
Marital status | 0.145 | |||
Married/Cohabiting | 4211 (71.2%) | 2816 (72.2%) | 1395 (69.0%) | |
Never married | 878 (11.9%) | 545 (11.4%) | 333 (12.9%) | |
Widowed/Divorced/Separated | 1266 (16.9%) | 781 (16.3%) | 485 (18.0%) | |
Family PIR | < 0.001 | |||
≤ 1.3 | 1494 (14.8%) | 893 (13.4%) | 601 (17.8%) | |
1.3–3.5 | 2152 (30.3%) | 1357 (29.3%) | 795 (32.3%) | |
> 3.5 | 1946 (45.6%) | 1415 (48.8%) | 531 (38.8%) | |
Smoking status | 0.098 | |||
Nonsmokers | 3829 (57.9%) | 2545 (59.1%) | 1284 (55.5%) | |
Former smokers | 1399 (25.2%) | 926 (25.3%) | 473 (25.1%) | |
Current smokers | 1127 (16.8%) | 672 (15.6%) | 455 (19.4%) | |
Drinking status | 0.149 | |||
Never drinking in the past year | 1697 (20.8%) | 1056 (19.8%) | 641 (23.0%) | |
Drinking in the past year | 4305 (74.3%) | 2851 (75.3%) | 1454 (72.4%) | |
Physical activity (≥ 600 MET-minutes/week) | 3976 (67.6%) | 2687 (70.1%) | 1289 (62.5%) | 0.001 |
High dietary quality | 2287 (37.8%) | 1607 (40.9%) | 680 (31.3%) | < 0.001 |
Decreased HDL | 4938 (47.15%) | 1082 (37.22%) | 3856 (50.96%) | < 0.001 |
BMI (kg/m2) | < 0.001 | |||
< 25 | 1501 (24.7%) | 1290 (31.6%) | 211 (10.3%) | |
25–30 | 2081 (33.0%) | 1565 (37.5%) | 516 (23.8%) | |
≥ 30 | 2569 (39.9%) | 1175 (29.1%) | 1394 (62.3%) | |
Elevated FPG | 2148 (31.1%) | 1258 (27.8%) | 890 (38.0%) | < 0.001 |
Low HDL | 2639 (39.2%) | 1535 (34.5%) | 1104 (49.0%) | < 0.001 |
High blood pressure | 2902 (40.9%) | 1766 (37.8%) | 1136 (47.2%) | < 0.001 |
Short sleep | 629 (7.4%) | 384 (6.7%) | 245 (9.0%) | < 0.001 |
Depression | 1351 (19.8%) | 756 (17.6%) | 595 (24.3%) | < 0.001 |
Self-reported oral health | < 0.001 | |||
Poor or fair | 2265 (28.3%) | 1351 (26.2%) | 914 (32.7%) | |
Good | 2093 (32.3%) | 1359 (30.7%) | 734 (35.7%) | |
Very good or excellent | 2000 (39.3%) | 1434 (43.1%) | 566 (31.5%) | |
Number of lost teeth | 2.8 ± 4.7 | 2.5 ± 4.4 | 3.3 ± 5.1 | 0.001 |
Interdental cleaning frequency (days/week) | 3.6 ± 2.8 | 3.8 ± 2.9 | 3.3 ± 2.8 | 0.004 |
Time since the last dental visit | < 0.001 | |||
6 months or less | 2552 (47.2%) | 1765 (49.9%) | 787 (41.7%) | |
6 months − 2 years | 1839 (26.2%) | 1177 (25.3%) | 662 (28.1%) | |
More than 2 years | 1967 (26.6%) | 1202 (24.8%) | 765 (30.2%) | |
Scaling and root planing treatment | 1691 (24.2%) | 1108 (24.2%) | 583 (24.4%) | 0.594 |
Serum high-sensitivity CRP (mg/L) | 3.4 ± 5.4 | 1.2 ± 0.8 | 8.1 ± 7.6 | < 0.001 |