Table 1 Baseline characteristics of reports on drug-associated myocarditis and pericarditis diseases adverse events.
From: Top 10 drugs most frequently associated with adverse events of myocarditis and pericarditis
Variables | Myocarditis, number (%) | Pericarditis, number (%) | |
|---|---|---|---|
Region reporting | African Region | 30 (0.09) | 18 (0.07) |
Region of the Americas | 18,067 (51.59) | 12,211 (48.92) | |
Southeast Asia Region | 44 (0.13) | 7 (0.03) | |
European Region | 11,869 (33.89) | 8,645 (34.64) | |
Eastern Mediterranean Region | 28 (0.08) | 26 (0.10) | |
Western Pacific Region | 4,979 (14.22) | 4,052 (16.23) | |
Reporting year | 1968–1979 | 0 (0) | 5 (0.02) |
1980–1989 | 3 (0.01) | 24 (0.10) | |
1990–1999 | 88 (0.25) | 99 (0.40) | |
2000–2009 | 705 (2.01) | 340 (1.36) | |
2010–2019 | 3,651 (10.43) | 1,933 (7.74) | |
2020–2024 | 30,570 (87.3) | 22,558 (90.38) | |
Reporter qualification | Health professional | 23,241 (66.37) | 14,251 (57.10) |
Non-health professional | 11,776 (33.63) | 10,708 (42.90) | |
Sex | Male | 23,407 (66.84) | 13,324 (53.38) |
Female | 11,118 (31.75) | 11,433 (45.81) | |
Unknown | 492 (1.41) | 202 (0.81) | |
Age, years | 0 to 17 | 2921 (8.34) | 1,058 (4.24) |
18 to 44 | 15,526 (44.34) | 9,954 (39.88) | |
45 to 64 | 5,885 (16.81) | 5,797 (23.23) | |
65 to 74 | 1,642 (4.69) | 1,357 (5.44) | |
≥ 75 | 1,018 (2.91) | 782 (3.13) | |
Unknown | 8,025 (22.92) | 6,011 (24.08) | |
TTO, days | Median days (IQR) | 1 (1–1) | 1 (1–1) |
Mean (SD) | 9.52 (62.68) | 6.46 (44.78) | |
Outcomes | Recovered | 10,864 (31.02) | 8,216 (32.92) |
Not recovered | 4,703 (13.43) | 4,697 (18.82) | |
Fatal | 741 (2.11) | 119 (0.48) | |
Unknown | 18,709 (53.43) | 11,927 (47.79) | |
Single drug suspected | 35,017 (100.00) | 24,959 (100.00) | |
