Fig. 1

CIAPIN1 expression was upregulated in endometrial cancer tissue and serum samples. (A) Endometrial cancer and adjacent normal tissues were stained with HE and CIAPIN1 expression was evaluated using immunohistochemistry (magnification, 200×). Typical images of CIAPIN1 low and CIAPIN1 high expression are shown. ELISA was performed to measure and compare the serum concentrations of CIAPIN1 (B) between patients with endometrial cancer (n = 113) and healthy controls (n = 60), and (C) between patients with endometrial cancer with CIAPIN1 low expression (n = 42) and CIAPIN1 high expression (n = 71). (D) RT-qPCR was performed to determine the mRNA expression of CIAPIN1 in frozen endometrial cancer tissues (n = 10) and adjacent normal tissues (n = 10). (E) Western blotting was performed to determine the protein expression of CIAPIN1 in endometrial cancer tissues (n = 4) and adjacent normal tissues (n = 4). Data are expressed as mean ± SD and were analyzed using the Student’s t-test. ***P < 0. 001 vs. the control or CIAPIN1 low-expression group.