Table 3 Results of GSEA for GSE135917.

From: Polygenic insight identifies precision biomarkers decoding protein catabolism and autophagy pathways in obstructive sleep apnea

ID

Set size

Enrichment score

NES

p value

p. adjust

q value

REACTOME_NEGATIVE_REGULATION_OF_NOTCH4_SIGNALING

48

0.714747

3.500093

1.00E − 10

7.06E − 09

4.87E − 09

REACTOME_AUF1_HNRNP_D0_BINDS_AND_DESTABILIZES_MRNA

48

0.663494

3.249106

1.00E − 10

7.06E − 09

4.87E − 09

REACTOME_HEDGEHOG_LIGAND_BIOGENESIS

59

0.57964

3.022846

1.00E − 10

7.06E − 09

4.87E − 09

REACTOME_METABOLISM_OF_POLYAMINES

55

0.617571

2.995692

1.00E − 10

7.06E − 09

4.87E − 09

REACTOME_CELLULAR_RESPONSE_TO_HYPOXIA

67

0.562945

2.97897

1.00E − 10

7.06E − 09

4.87E − 09

REACTOME_REGULATION_OF_PTEN_STABILITY_AND_ACTIVITY

63

0.579141

2.972406

1.00E − 10

7.06E − 09

4.87E − 09

WP_INHIBITION_OF_EXOSOME_BIOGENESIS_AND_SECRETION_BY_MANUMYCIN_A_IN_CRPC_CELLS

17

0.762878

2.923725

2.29E − 07

7.82E − 06

5.40E − 06

REACTOME_STABILIZATION_OF_P53

50

0.60138

2.855201

1.00E − 10

7.06E − 09

4.87E − 09

REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS

77

0.547256

2.83186

1.00E − 10

7.06E − 09

4.87E − 09

REACTOME_SIGNALING_BY_NOTCH4

75

0.558014

2.831114

1.00E − 10

7.06E − 09

4.87E − 09

WP_GLYCOLYSIS_IN_SENESCENCE

11

0.831112

2.723285

3.93E − 06

9.26E − 05

6.38E − 05

WP_OXIDATIVE_PHOSPHORYLATION

37

0.563414

2.595978

2.18E − 07

7.70E − 06

5.31E − 06

WP_EXERCISEINDUCED_CIRCADIAN_REGULATION

42

0.509185

2.484184

8.60E − 07

2.63E − 05

1.81E − 05

WP_MITOCHONDRIAL_LONG_CHAIN_FATTY_ACID_BETAOXIDATION

17

0.632757

2.42504

5.80E − 05

0.000824

0.000568

WP_HOSTPATHOGEN_INTERACTION_OF_HUMAN_CORONAVIRUSES_AUTOPHAGY

19

0.605215

2.404119

6.13E − 05

0.000855

0.00059

REACTOME_SELECTIVE_AUTOPHAGY

66

0.448255

2.385601

3.05E − 08

1.33E − 06

9.15E − 07

WP_METABOLIC_REPROGRAMMING_IN_COLON_CANCER

37

0.511911

2.358671

5.46E − 06

0.000122

8.43E − 05

PID_TGFBR_PATHWAY

49

0.467776

2.290069

6.53E −  − 07

2.08E − 05

1.43E − 05

REACTOME_TP53_REGULATES_METABOLIC_GENES

80

0.426929

2.278438

9.56E − 09

4.80E − 07

3.31E − 07

REACTOME_CHAPERONE_MEDIATED_AUTOPHAGY

20

0.56754

2.251265

0.000213

0.002345

0.001618

  1. GSEA Gene Set Enrichment Analysis.
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