Table 5 Results of GSEA for risk groups.

From: Polygenic insight identifies precision biomarkers decoding protein catabolism and autophagy pathways in obstructive sleep apnea

ID

Set Size

Enrichment Score

NES

pvalue

p.adjust

qvalue

REACTOME_NEGATIVE_REGULATION_OF_NOTCH4_SIGNALING

48

0.720522

3.695955

1.00E − 10

6.44E − 09

4.56E − 09

REACTOME_AUF1_HNRNP_D0_BINDS_AND_DESTABILIZES_MRNA

48

0.689892

3.538839

1.00E − 10

6.44E − 09

4.56E − 09

BYSTROEM_CORRELATED_WITH_IL5_DN

57

0.58871

3.283267

1.00E − 10

6.44E − 09

4.56E − 09

REACTOME_REGULATION_OF_PTEN_STABILITY_AND_ACTIVITY

63

0.606667

3.212892

1.00E − 10

6.44E − 09

4.56E − 09

REACTOME_METABOLISM_OF_POLYAMINES

55

0.594897

3.209871

1.00E − 10

6.44E − 09

4.56E − 09

REACTOME_STABILIZATION_OF_P53

50

0.611983

3.207074

1.00E − 10

6.44E − 09

4.56E − 09

REACTOME_SIGNALING_BY_NOTCH4

75

0.563487

3.201288

1.00E − 10

6.44E − 09

4.56E − 09

REACTOME_HEDGEHOG_LIGAND_BIOGENESIS

59

0.562063

3.198313

1.00E − 10

6.44E − 09

4.56E − 09

REACTOME_CELLULAR_RESPONSE_TO_HYPOXIA

67

0.5642

3.139325

1.00E − 10

6.44E − 09

4.56E − 09

REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS

77

0.545974

3.099099

1.00E − 10

6.44E − 09

4.56E − 09

WP_MITOCHONDRIAL_FATTY_ACID_OXIDATION_DISORDERS

19

0.763648

3.007781

2.41E − 08

9.16E − 07

6.50E − 07

WP_FATTY_ACID_BIOSYNTHESIS

21

0.744851

2.973303

2.98E − 08

1.10E − 06

7.80E − 07

RAHMAN_TP53_TARGETS_PHOSPHORYLATED

17

0.782156

2.916072

1.04E − 07

3.48E − 06

2.47E − 06

WP_METABOLIC_REPROGRAMMING_IN_COLON_CANCER

37

0.576786

2.842185

4.60E − 08

1.63E − 06

1.15E − 06

SAKAI_TUMOR_INFILTRATING_MONOCYTES_DN

72

0.489578

2.833951

1.13E − 10

7.05E − 09

5.00E − 09

REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE

54

0.511493

2.808144

5.08E − 09

2.25E − 07

1.60E − 07

WP_MITOCHONDRIAL_LONG_CHAIN_FATTY_ACID_BETA_OXIDATION

17

0.735278

2.741301

1.26E − 06

3.06E − 05

2.17E − 05

GENTILE_UV_LOW_DOSE_DN

60

0.49164

2.737177

4.56E − 09

2.07E − 07

1.47E − 07

WP_FATTY_ACID_BETA_OXIDATION

30

0.601567

2.719223

2.90E − 07

8.64E − 06

6.12E − 06

MILI_PSEUDOPODIA

39

0.532567

2.703576

3.17E − 07

9.36E − 06

6.63E − 06

  1. GSEA Gene Set Enrichment Analysis.
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