Table 2 Demographics of neonates with NE.
From: Childhood resolution of early abnormal miRNA following neonatal encephalopathy
Clinical characteristics and birth history of NE cohort | ||
|---|---|---|
Neonates (n = 10) | Children (n = 11) | |
Gestational Age, median (IQR), weeks | 39 (2.7) | 40.3 (1.5) |
Birth weight, median (IQR), kgs | 3.5 (0.9) | 3.4 (0.65) |
Mode of Delivery, n (%) | ||
SVD | 4 (40) | 2 (18) |
Inst | 2 (20) | 3 (27) |
LSCS | 2 (10) | 6 (55) |
Apgar, median (IQR) | ||
@ 1 min | 4 (1.5) | 2 (1.5) |
@ 5 min | 5.5 (2.8) | 6 (3.5) |
@ 10 min | 7 (2.0) | 7 (4.25) |
Sarnat Scoring, n (%) | ||
Grade 1 | 2 (20) | 1 (9) |
Grade 2 | 5 (50) | 8 (73) |
Grade 3 | 3 (30) | 2 (18) |
TH, n (%), Yes | 9 (90) | 10 (91) |
Seizures, n (%), Yes | 6 (60) | 5 (45) |
MRI - Abnormal, n (%) | ||
Normal | 4 (40) | 4 (36) |
Abnormal | 4 (40) | 5 (45) |
Not performed | 2 (20) | 2 (18) |
Cord pH (arterial), median (IQR) | 6.95 (0.2) | 6.93 (0.09) |
Initial Lactate, median (IQR) | 11.2 (5.8) | 12.42 (4.62) |
Clinical assessment of follow-up Children cohort | ||
Control (n = 12) | NE (n = 11) | |
Age - months, median (IQR) | 49.5 (22) | 44 (19) |
Clinical development assessment, n (%), Abnormal | ||
Gross motor | 0 (0) | 2 (18) |
Vision and fine motor | 0 (0) | 1 (9) |
Hearing, speech and language | 0 (0) | 3 (27) |
Social, emotional and behavioural | 0 (0) | 2 (18) |
PedQL, median (IQR) | 85.1 (6.3) | 88.1 (14.29) |
