Fig. 4 | Scientific Reports

Fig. 4

From: CPS1-promoted the progression of lung adenocarcinoma via suppressing ammonia induced the activation of ROS/AMPK/P53/LKB1 signaling pathway

Fig. 4

CPS1 knockdown inhibits the growth of transplanted tumors in nude mice through the AMPK/P53 pathway (A): The experimental tumor results of subcutaneous tumor transplantation in nude mice for the NC group, CPS1-KD group, CPS1-KD + AMPK-OE group, CPS1-KD + AMPK-OE + P53-KD group, CPS1-KD + AMPK-KD group and CPS1-KD + AMPK-KD + P53-OE group; (B): Statistical graphs of tumor volume and tumor weight for each group.N = 6, P < 0.05 is considered statistically significant. nsP > 0.05; *P < 0.05; **P < 0.01.

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