Table 2 Association between age and each serum protein concentration showing significant differences by sex.

			Men			Women
Sequence ID	Full Name	Entrez Gene Name	β	SE	p-value	β	SE	p-value
2953-31	Luteinizing hormone	CGA\|LHB	0.006	0.016	0.706	-0.006	0.018	0.736
3032-11	Follicle stimulating hormone	CGA\|FSHB	0.003	0.029	0.908	0.023	0.016	0.163
4914-10	Human Chorionic Gonadotropin	CGA\|CGB3\|CGB7	-0.005	0.023	0.840	-0.014	0.030	0.646
5763-67	Beta-defensin 104	DEFB104A	-0.004	0.015	0.776	-0.006	0.004	0.163
2788-55	Stromelysin-1	MMP3	0.007	0.016	0.674	-0.020	0.018	0.283
4330-4	Prostate-specific antigen	KLK3	0.010	0.013	0.464	0.002	0.007	0.823
5457-5	Collectin-12	COLEC12	0.015	0.010	0.181	0.004	0.013	0.781
5680-54	Odorant-binding protein 2b	OBP2B	0.011	0.014	0.450	-0.006	0.006	0.345
6965-19	Contactin-associated protein-like 2	CNTNAP2	0.009	0.007	0.214	0.005	0.006	0.453
8814-33	Proactivator polypeptide-like 1	PSAPL1	0.009	0.012	0.485	-0.021	0.017	0.216
8428-102	Neurotrimin	NTM	0.016	0.007	0.039	0.009	0.010	0.383
21685-29	DCC	DCC	0.017	0.014	0.217	0.016	0.020	0.433
19372-7	MAM domain-containing glycosylphosphatidylinositol anchor protein 2	MDGA2	0.010	0.012	0.446	0.002	0.013	0.873
2974-61	Contactin-1	CNTN1	0.008	0.007	0.281	0.009	0.008	0.258
20912-10	Pseudouridine-5’-phosphatase	PUDP	0.012	0.007	0.104	0.019	0.010	0.084
17678-28	V-set and immunoglobulin domain-containing protein 4	VSIG4	0.017	0.015	0.256	0.023	0.009	0.020
6392-7	WNT1-inducible-signaling pathway protein 2	CCN5	0.000	0.008	0.984	-0.007	0.009	0.423
19558-10	Low-density lipoprotein receptor-related protein 4	LRP4	0.016	0.008	0.065	0.010	0.008	0.238
9482-110	ADP-ribose pyrophosphatase, mitochondrial	NUDT9	-0.003	0.006	0.667	0.000	0.007	0.998
9269-7	Biotinidase	BTD	-0.007	0.004	0.092	-0.004	0.006	0.484

The simple linear regression was used to calculate the standardized coefficient (β) and standard error (SE) in male and female groups.

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