Table 1 Baseline characteristics of the study population.
Variables | Total (n = 16,785) | Hyperuricemia | P-value | |
|---|---|---|---|---|
No (n = 13,213) | Yes (n = 3,572) | |||
Age, years, mean (Q₁, Q₃) | 50.00 (33.00, 64.00) | 47.00 (32.00, 63.00) | 58.00 (40.00, 69.00) | < 0.001 |
Gender, n (%) | < 0.001 | |||
Male | 8413 (50.12) | 6473 (48.99) | 1940 (54.31) | |
Female | 8372 (49.88) | 6740 (51.01) | 1632 (45.69) | |
Race, n (%) | < 0.001 | |||
Mexican American | 2778 (16.55) | 2367 (17.91) | 411 (11.51) | |
Other Hispanic | 1657 (9.87) | 1377 (10.42) | 280 (7.84) | |
Non-Hispanic White | 7128 (42.47) | 5521 (41.78) | 1607 (44.99) | |
Non-Hispanic Black | 3485 (20.76) | 2596 (19.65) | 889 (24.89) | |
Other race/multiracial | 1737 (10.35) | 1352 (10.23) | 385 (10.78) | |
Education Level, n (%) | 0.66 | |||
Less Than 9th Grade | 1640 (10.33) | 1309 (10.53) | 331 (9.60) | |
9-11th Grade | 2304 (14.51) | 1825 (14.68) | 479 (13.89) | |
High School Grad/GED or Equivalent | 3660 (23.05) | 2817 (22.67) | 843 (24.44) | |
Some College or AA degree | 4638 (29.21) | 3562 (28.66) | 1076 (31.20) | |
College Graduate or above | 3635 (22.89) | 2915 (23.46) | 720 (20.88) | |
Poverty ratio, n (%) | 0.017 | |||
Low income ≤ 1.3 | 4917 (31.91) | 3938 (32.47) | 979 (29.86) | |
Middle income (1.31–3.5) | 5861 (38.04) | 4574 (37.71) | 1287 (39.25) | |
High income (>3.5) | 4629 (30.04) | 3616 (29.82) | 1013 (30.89) | |
BMI, kg/m2, mean (Q₁, Q₃) | 28.00 (24.30, 32.66) | 27.30 (23.80, 31.60) | 31.10 (27.20, 36.50) | < 0.001 |
Serum uric acid level, mg/dL, mean (Q₁, Q₃) | 5.40 (4.50, 6.40) | 5.00 (4.20, 5.70) | 7.30 (6.80, 8.00) | < 0.001 |
Circadian Syndrome Score, mean (Q₁, Q₃) | 3.00 (1.00, 4.00) | 2.00 (1.00, 4.00) | 4.00 (2.00, 5.00) | < 0.001 |
Circadian Syndrome, n (%) | < 0.001 | |||
No | 10,952 (65.25) | 9257 (70.06) | 1695 (47.45) | |
Yes | 5833 (34.75) | 3956 (29.94) | 1877 (52.55) | |
Components of Circadian Syndrome | ||||
Triglyceride, n (%) | < 0.001 | |||
No | 9818 (58.49) | 8268 (62.57) | 1550 (43.39) | |
Yes | 6967 (41.51) | 4945 (37.43) | 2022 (56.61) | |
HDL-C, n (%) | < 0.001 | |||
No | 9415 (56.09) | 7844 (59.37) | 1571 (43.98) | |
Yes | 7370 (43.91) | 5369 (40.63) | 2001 (56.02) | |
Blood glucose, n (%) | < 0.001 | |||
No | 7368 (43.90) | 6330 (47.91) | 1038 (29.06) | |
Yes | 9417 (56.10) | 6883 (52.09) | 2534 (70.94) | |
Waist circumference, n (%) | < 0.001 | |||
No | 7236 (43.11) | 6297 (47.66) | 939 (26.29) | |
Yes | 9549 (56.89) | 6916 (52.34) | 2633 (73.71) | |
Depression symptoms, n (%) | 0.279 | |||
No | 15,352 (91.46) | 12,101 (91.58) | 3251 (91.01) | |
Yes | 1433 (8.54) | 1112 (8.42) | 321 (8.99) | |
Sleep health, n (%) | < 0.001 | |||
No | 14,438 (86.02) | 11,429 (86.50) | 3009 (84.24) | |
Yes | 2347 (13.98) | 1784 (13.50) | 563 (15.76) | |
Blood pressure, n (%) | < 0.001 | |||
No | 8792 (52.38) | 7608 (57.58) | 1184 (33.15) | |
Yes | 7993 (47.62) | 5605 (42.42) | 2388 (66.85) | |
Albumin, g/L, mean (Q₁, Q₃) | 42.00 (40.00, 44.00) | 42.00 (40.00, 44.00) | 42.00 (40.00, 44.00) | < 0.001 |
ALT, U/L, mean (Q₁, Q₃) | 20.00 (16.00, 28.00) | 20.00 (15.00, 27.00) | 23.00 (17.00, 32.00) | < 0.001 |
AST, U/L, mean (Q₁, Q₃) | 22.00 (19.00, 27.00) | 22.00 (19.00, 27.00) | 24.00 (20.00, 29.00) | < 0.001 |
eGFR, mL/min/1.73m2, mean (Q₁, Q₃) | 82.09 (64.29, 100.77) | 85.89 (68.33, 103.95) | 68.19 (51.71, 85.98) | < 0.001 |
Cancer, n (%) | < 0.001 | |||
Yes | 1533 (9.66) | 1108 (8.92) | 425 (12.32) | |
No | 14,344 (90.34) | 11,319 (91.08) | 3025 (87.68) | |
Stroke, n (%) | < 0.001 | |||
Yes | 632 (3.98) | 420 (3.38) | 212 (6.15) | |
No | 15,239 (96.02) | 12,004 (96.62) | 3235 (93.85) | |
Coronary heart disease, n (%) | < 0.001 | |||
Yes | 776 (4.90) | 526 (4.24) | 250 (7.29) | |
No | 15,047 (95.10) | 11,867 (95.76) | 3180 (92.71) | |
Alcohol, n (%) | 0.931 | |||
Yes | 11,979 (73.49) | 9396 (73.48) | 2583 (73.55) | |
No | 4321 (26.51) | 3392 (26.52) | 929 (26.45) | |
Smoke, n (%) | < 0.001 | |||
Yes | 7349 (45.39) | 5657 (44.57) | 1692 (48.33) | |
No | 8843 (54.61) | 7034 (55.43) | 1809 (51.67) | |
