Table 5 Arterial lactate and clinical severity of HIE.

From: The significance of glycemic variability in conjunction with lactate metabolism levels in the clinical assessment of neonatal hypoxic-ischemic encephalopathy

 

Mild

n = 20

Moderate

n = 12

Severe

n = 6

Moderate-severe

n = 18

F

P-value

LAC TP0 (mmol/L)

6.9 ± 2.7

7.7 ± 2.6

8.7 ± 4.6

8.0 ± 3.3

0.701

0.556

LAC TP6 (mmol/L)

3.6 ± 2.4

4.7 ± 1.7

7.1 ± 4.0

5.6 ± 2.8

3.496

0.022

LCR (%)

49.0 ± 16.7

36.6 ± 17.5

19.8 ± 7.2

31.0 ± 16.7

6.705

0.001

  1. HIE, hypoxic-ischemic encephalopathy; LAC, lactate; TP0, time point of admission, the timing of LACTP0 corresponded to within 0.5 h post-birth; TP6, time point 6 h after admission, the timing of LACTP6 corresponded to approximately 6 h post-birth; LCR, lactate clearance rate.
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