Table 2 Digital health technology assessment evaluating walking and turning in LO-GSDII compared to matched control subjects. The assessment evaluated gait and turning parameters. Abbreviations: TUG, timed up and go test.

From: Extensive digital health technology assessment detects subtle motor impairment in mild and asymptomatic Pompe disease

Parameter

LO-GSDII patients (n = 8)

Healthy controls (n = 52)

P-value

Walking normal speed

Step counts (n)

578 (± 136.34)

710 (± 56.59)

0.02

Step time (s)

0.67 (± 0.28)

0.51 (± 0.38)

< 0.001

Step time variability (s)

0.07 (± 0.03)

0.04 (± 0.01)

< 0.001

Step asymmetry

0.02 (± 0.01)

0.01 (± 0.10)

0.27

Step Length

0.61 (± 0.14)

0.69 (± 0.07)

0.05

Turning during TUG

Angle of turns (grades)

179.52 (± 16.02)

183.25 (± 26.10)

0.58

Duration turning (sec)

2.33 (± 0.58)

2.22 (± 0.58)

0.17

Angular velocity (rad/s)

79.83 (± 20.31)

90.76 (± 16.55)

0.02

Peak angular velocity (rad/s)

176.79 (± 43.23)

213.25 (± 36.62)

0.01

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