Table 3 Cox proportional hazards regression analysis of the effects of multiple variables on survival in patients with PM.

From: Reduced serum iron levels predict poor prognosis in pulmonary mucormycosis patients: a prospective, case‒control study

Variables

Univariate analysis

Multivariate analysis

HR (95% CI)

p value

HR (95% CI)

p value

Age (years)

1.028 (0.980–1.079)

0.26

 

-

Male

0.549 (0.146–2.062)

0.375

 

-

Smoking

2.463 (0.658–9.218)

0.181

 

-

Duration in days of preadmission symptoms

0.945 (0.812-1.100)

0.466

 

-

Antibiotic pretreatment

0.570 (0.118–2.768)

0.486

 

-

Liver (or kidney) transplantation status

2.035 (0.419–9.874)

0.378

  

Hematopoietic stem cell transplantation status

1.059 (0.849–1.320)

0.612

  

Malignant tumor in treatment

0.750 (0.155–3.620)

0.72

  

Diabetes mellitus

0.827 (0.205–3.338)

0.79

 

-

Malignant tumor in treatment

0.750 (0.155–3.620)

0.72

 

-

WBC (×109/L)

0.955 (0.794–1.149)

0.955

 

-

CRP (mg/L)

1.004 (0.997–1.012)

0.287

 

-

PCT (mg/L)

1.356 (1.061–1.732)

0.015

1.980 (1.283–3.057)

0.002

IL-6 (ng/L)

1.005 (1.001–1.010)

0.05

 

-

Serum iron (µmol/L)

0.913 (0.839–0.982)

0.041

0.872 (0.784–0.969)

0.011

Serum ferritin (µg/L)

1.000 (1.000–1.000)

0.447

  

Unsaturated iron-binding capacity (µmol/L)

0.980 (0.912–1.054)

0.59

 

-

Total iron-binding capacity (µmol/L)

0.973 (0.917–1.032)

0.357

 

-

Percentage transferrin saturation (%)

0.975 (0.930–1.024)

0.312

 

-

Hemoglobin (g/L)

0.974 (0.943–1.005)

0.099

 

-

  1. WBC white blood cell; CRP C-reactive protein; PCT procalcitonin; IL-6 interleukin-6.