Table 1 Experimental groups for the comparative (A) and validation (B) study.
(A) Group | Animals (n) | Antibody (dose) | Administration method | Time of euthanasia (hours post-immunization) | Disease status |
|---|---|---|---|---|---|
1 | 4 | IgG1 anti-β-Gal-rIgG (0.5 mg/kg) | I.P. | 48 | Non-MG |
2 | 4 | IgG1 anti-β-Gal-rIgG (0.5 mg/kg) | S.C. | 48 | Non-MG |
3 | 5 | mAb35 (20 ρmol/100 g BW; 0.03 mg/kg) | I.P. | 48 | PTMG |
4 | 7 | mAb35 (20 ρmol/100 g BW; 0.03 mg/kg) | S.C. | 48 | PTMG |
5 | 6 | mAb35 (20 ρmol/100 g BW; 0.03 mg/kg) | S.C. | 72 | PTMG |
6 | 6 | mAb35 (40ρmol/100 g BW; 0.06 mg/kg) | S.C. | 48 | PTMG |
(B) Group | Animals (n) | Antibody (dose) | Administration method | Time of euthanasia (hours post-immunization) | Disease status |
|---|---|---|---|---|---|
1 | 4 | Saline | S.C. | 48 | Non-MG |
2 | 8 | mAb35 (40 ρmol/100 g BW; 0.06 mg/kg) | S.C. | 48 | PTMG |
