Table 5 Experimentally verified target genes associated with differentially regulated miRNAs.

hsa-miR-30c-5p

40

SNAI1, SERPINE1, UBE2I, SMAD1, IL11, VIM, TWF1, MTA1, HSPA4, TGIF2, HDAC4, SOCS3, BCL9, DDIT4, DLL4, CCND2, IDH1, RARB, NCOR2, RFX6, CASP3, RUNX2, JAK1, MTTP, SNAI2, NOTCH1, TP53, FASN, EIF2S1, BECN1, DNMT1, RASAL2, CAMK2D, IER2, CDC42, PAK1, FOXO3, CTGF, MCL1, TRADD

hsa-miR-335-3p

5

NOS3, ESR1, PAX6SP1, MET, SP1

hsa-miR-132-3p

34

ARHGAP32, SIRT1, CDKN1A, RB1, CRK, HBEGF, RASA1, TJAP1, TLN2, SPRED1, MUC13, CCNA2, CCNB1, FOXO1, JPT1, BDNF, KLHL11, MAPK1, SOX4, SOX5, IRAK4, EGFR, RAF1, SPRY1, MMP9, GDF5, YY1AP1, AGO2, PIK3R3, SOX6, SMAD2, SLC2A1, FOXO3, PTEN,

hsa-miR-127-3p

18

MAPK4, MMP13, PRDM1, XBP1, BCL6, KMT5A, XRCC3, SKI, SEPT7, RGMA, ZWINT, SFRP1, SERPINB9, MGMT, BAG5, IGF1R, IRS1, BLVRB

hsa-miR-103a-2-5p

2

SMAD4, PDCD10

hsa-miR-146b-3p

5

PER1, MAT2A, NPAS4, IRAK1, SMAD4

hsa-miR-202-5p

3

TGFBR1, TGFBR2, TNFSF13B

hsa-miR-18a-3p

7

KRAS, CBX7, ATM, HIF1α, IRF2, S6k1, 4EBPL

hsa-miR-154-5p

6

TLR2, ZEB2, HMGA2, CCND2, WNT5A, E2F5

hsa-miR-28-3p

2

STAT5B, TP53, BAG1, IGF1